Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13537323 | 0.99 | ALOX5 (0.42) | ALOX5KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL13537346 | 0.91 | KMT2A (0.44) | ALOX5KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL13537324 | 0.89 | ALOX5 (0.46) | ALOX5KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL3358211 | 0.78 | MAPT (0.47) | ALOX5KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL3351542 | 0.77 | ALDH1A1 (0.46) | ALOX5KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL13537325 | 0.75 | ALDH1A1 (0.42) | KMT2AALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2075770 | 0.71 | POLB (0.47) | ALOX5KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL3353911 | 0.70 | ALDH1A1 (0.45) | KMT2AALDH1A1RAB9ANPC1L3MBTL1 | |
| SCHEMBL1559389 | 0.69 | KMT2A (0.65) | ALOX5KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL13537395 | 0.69 | HTR6 (0.43) | HTR2AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |