Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 20/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 7/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13537609 | 0.81 | KDM4E (0.46) | CYP2C9 | |
| SCHEMBL3354522 | 0.80 | GRIN2B (0.45) | GRIN2BGRIN1CYP2C9 | |
| SCHEMBL13537340 | 0.76 | DRD2 (0.40) | — | |
| SCHEMBL8568248 | 0.76 | KMT2A (0.65) | GRIN2B | |
| SCHEMBL3356633 | 0.76 | HTR7 (0.50) | GRIN2BGRIN1 | |
| SCHEMBL13537353 | 0.76 | PTGS2 (0.40) | GRIN2B | |
| SCHEMBL21936469 | 0.72 | GRIN2B (0.55) | GRIN2BGRIN1 | |
| SCHEMBL20939415 | 0.70 | GRIN2B (0.43) | GRIN2BGRIN1CYP2C9 | |
| SCHEMBL13222511 | 0.69 | CYP2A6 (0.53) | — | |
| SCHEMBL23799893 | 0.69 | GRIN2B (0.51) | GRIN2BGRIN1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |