Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 9/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3353889 | 0.82 | HRH4 (0.49) | PTGS2HTR7KMT2AUSP2ALDH1A1 | |
| SCHEMBL12605568 | 0.79 | KMT2A (0.56) | PTGS2KMT2AALDH1A1HSD17B10MAPT | |
| SCHEMBL3356853 | 0.79 | HTR7 (0.62) | HTR7KMT2AALDH1A1MEN1HPGD | |
| SCHEMBL13537316 | 0.76 | HTR7 (0.41) | HTR7 | |
| SCHEMBL13537609 | 0.76 | KDM4E (0.46) | KMT2AUSP2ALDH1A1HPGDTSHR | |
| SCHEMBL13537401 | 0.76 | GRIN2B (0.43) | GRIN2B | |
| SCHEMBL13537343 | 0.72 | HTR7 (0.38) | HTR7 | |
| SCHEMBL29930457 | 0.70 | GRIN2B (0.60) | GRIN2B | |
| SCHEMBL11988944 | 0.69 | NOS3 (0.53) | HTR7 | |
| SCHEMBL20604929 | 0.68 | ROCK1 (0.41) | PTGS2HTR7KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |