Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.42 |
| ▸ | CACNB4 | O00305 | 5/20 | 0.41 |
| ▸ | CACNA1A | O00555 | 5/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 5/20 | 0.41 |
| ▸ | CACNG3 | O60359 | 5/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 5/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 5/20 | 0.41 |
| ▸ | CACNB3 | P54284 | 5/20 | 0.41 |
| ▸ | CACNA2D1 | P54289 | 5/20 | 0.41 |
| ▸ | CACNG7 | P62955 | 5/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 5/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 5/20 | 0.41 |
| ▸ | CACNB1 | Q02641 | 5/20 | 0.41 |
| ▸ | CACNG1 | Q06432 | 5/20 | 0.41 |
| ▸ | CACNB2 | Q08289 | 5/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 5/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 5/20 | 0.41 |
| ▸ | CACNA1E | Q15878 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13537525 | 0.90 | LMNA (0.46) | LMNAGLAHRH3TSHRALDH1A1 | |
| SCHEMBL13537351 | 0.87 | HRH3 (0.55) | LMNAGLAHRH3KMT2ATSHR | |
| SCHEMBL13537417 | 0.82 | CACNB4 (0.41) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL3353653 | 0.80 | ACHE (0.50) | LMNAGLAHRH3CACNB4CACNA1A | |
| SCHEMBL13537252 | 0.78 | HTR6 (0.44) | HRH3GAAKDM4E | |
| SCHEMBL3357630 | 0.77 | ALDH1A1 (0.53) | LMNAHRH3CACNB4CACNA1ACACNA1G | |
| SCHEMBL13537395 | 0.76 | HTR6 (0.43) | HRH3GAA | |
| SCHEMBL5961922 | 0.76 | LMNA (0.69) | LMNAGLATSHRALDH1A1HDAC8 | |
| SCHEMBL13537350 | 0.75 | HTR2A (0.41) | LMNAALDH1A1HDAC8HDAC6 | |
| SCHEMBL13537524 | 0.72 | HRH3 (0.41) | HRH3KMT2AALDH1A1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |