Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA7 | P43166 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12212629 | 0.83 | DGAT1 (0.46) | NPSR1MAPTKMT2AMEN1LMNA | |
| SCHEMBL19203928 | 0.79 | CA12 (0.50) | MAPTKMT2AMEN1LMNACA12 | |
| SCHEMBL29699529 | 0.75 | NPSR1 (0.46) | NPSR1MAPTKMT2AMEN1LMNA | |
| SCHEMBL22444180 | 0.75 | NPSR1 (0.46) | NPSR1MAPTKMT2AMEN1LMNA | |
| SCHEMBL22444178 | 0.75 | NPSR1 (0.46) | NPSR1MAPTKMT2AMEN1LMNA | |
| SCHEMBL31294436 | 0.74 | CES2 (0.46) | NPSR1MAPTKMT2AMEN1LMNA | |
| SCHEMBL13537990 | 0.74 | MIF (0.42) | NPSR1MAPTKMT2AMEN1LMNA | |
| SCHEMBL10188266 | 0.74 | MEP1B (0.40) | NPSR1MAPTKMT2AMEN1LMNA | |
| SCHEMBL24047741 | 0.72 | SMN1; SMN2 (0.44) | NPSR1MAPTKMT2AMEN1CYP1A2 | |
| SCHEMBL10188264 | 0.71 | NPSR1 (0.41) | NPSR1MAPTKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010004198-A2 | ANTINEOPLASTIC DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2010-01-14 | — | — | WO | disclosed |