SCHEMBL1353817

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3583207	0.86	ROCK1 (0.38)	CDK4CCND1CCND2CCND3GSK3A
	SCHEMBL3593201	0.83	ROCK1 (0.36)	CDK4CCND1CCND2CCND3GSK3A
	SCHEMBL1353745	0.79	AURKA (0.53)	GSK3AGSK3BAURKAAURKB
	SCHEMBL1353795	0.77	DCLK1 (0.52)	CDK4CCND1CCND2CCND3CCNB2
	SCHEMBL1353840	0.77	CDK4 (0.54)	CDK4CCND1CCND2CCND3CCNE2
	SCHEMBL1356760	0.77	EIF2AK4 (0.57)	CDK4CCND1CCND2CCND3FGFR1
	SCHEMBL1355868	0.77	EIF2AK4 (0.46)	CDK4FGFR1FGFR2FGFR4FGFR3
	SCHEMBL1355881	0.76	STAT6 (0.57)	CDK4CCND1CCND2CCND3CCNB2
	SCHEMBL1355286	0.75	CDK4 (0.59)	CDK4CCND1CCND2CCND3CCNB2
	SCHEMBL1355558	0.75	CDK1 (0.48)	CDK4CCND1CCND2CCND3CCNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.