Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.65 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.65 |
| ▸ | ACHE | P22303 | 5/20 | 0.62 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.59 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.59 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | EDNRA | P25101 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | HTR2B | P41595 | 1/20 | 0.59 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.59 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.59 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13539758 | 0.89 | AGTR1 (0.66) | AGTR1LTB4R2ACHEABCC3ABCC4 | |
| SCHEMBL13539751 | 0.88 | AGTR1 (0.65) | AGTR1LTB4R2ACHEABCC3ABCC4 | |
| SCHEMBL13539734 | 0.88 | ACHE (0.61) | AGTR1LTB4R2ACHEABCC3ABCC4 | |
| SCHEMBL13539765 | 0.86 | ACHE (0.77) | AGTR1LTB4R2ACHEABCC3ABCC4 | |
| SCHEMBL13539763 | 0.85 | AGTR1 (0.61) | AGTR1LTB4R2ACHEABCC3ABCC4 | |
| SCHEMBL3483854 | 0.85 | AGTR1 (0.47) | AGTR1LTB4R2ACHE | |
| SCHEMBL13539541 | 0.85 | AGTR1 (0.62) | AGTR1LTB4R2ACHEABCC3ABCC4 | |
| SCHEMBL13539542 | 0.84 | AGTR1 (0.62) | AGTR1LTB4R2ACHEABCC3ABCC4 | |
| SCHEMBL13539732 | 0.84 | AGTR1 (0.66) | AGTR1LTB4R2ACHEABCC3ABCC4 | |
| SCHEMBL13539544 | 0.84 | AGTR1 (0.61) | AGTR1LTB4R2ACHEABCC3ABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100004159-A1 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATIONS AND USES | GENFIT (FR) | 2010-01-07 | — | — | US | disclosed |
| US-20100004159-A1 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATIONS AND USES | GENFIT (FR) | 2010-01-07 | — | — | US | disclosed |
| WO-2008012470-A2 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES | GENFIT (FR) | 2008-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004159-A1 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATIONS AND USES | IPO5, PPIP5K2, IPO4 | AGTR1 1691/4885LTB4R2 3646/4885ACHE 2077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.