Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.41 |
| ▸ | RHEB | Q15382 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10221867 | 0.77 | KDM4E (0.55) | KDM4EALDH1A1GPR84HTR2AIMPDH2 | |
| SCHEMBL835657 | 0.76 | KDM4E (0.53) | KDM4EALDH1A1NPSR1MAPT | |
| SCHEMBL21035552 | 0.76 | GPR84 (0.57) | KDM4EALDH1A1GPR84HTR2AIMPDH2 | |
| SCHEMBL1399520 | 0.75 | ALDH1A1 (0.46) | KDM4EALDH1A1GPR84HTR2AIMPDH2 | |
| SCHEMBL21027633 | 0.74 | KDM4E (0.56) | KDM4EALDH1A1GPR84HTR2AIMPDH2 | |
| SCHEMBL1399447 | 0.74 | HTR2A (0.55) | KDM4EALDH1A1GPR84HTR2AL3MBTL1 | |
| SCHEMBL1399471 | 0.74 | LMNA (0.57) | KDM4EALDH1A1 | |
| SCHEMBL17936381 | 0.73 | MAPT (0.48) | KDM4EALDH1A1GPR84IMPDH2HTT | |
| SCHEMBL575956 | 0.73 | HAO1 (0.52) | — | |
| SCHEMBL28543725 | 0.72 | KDM4E (0.50) | KDM4EALDH1A1GPR84HTR2AIMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7645774-B2 | Cannabinoid receptor ligands | SCHERING CORPORATION (US) | 2010-01-12 | — | — | US | disclosed |
| US-7645774-B2 | Cannabinoid receptor ligands | SCHERING CORPORATION (US) | 2010-01-12 | — | — | US | disclosed |