Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | IMPDH2 | P12268 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | GPR3 | P46089 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.47 |
| ▸ | CDK4 | P11802 | 1/20 | 0.47 |
| ▸ | CCND1 | P24385 | 1/20 | 0.47 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29473770 | 0.76 | GPR84 (0.57) | GPR84HTR2AALDH1A1IMPDH2HTT | |
| SCHEMBL10395712 | 0.76 | GPR84 (0.57) | GPR84HTR2AALDH1A1IMPDH2HTT | |
| SCHEMBL146530 | 0.76 | GPR84 (0.57) | GPR84HTR2AALDH1A1IMPDH2HTT | |
| SCHEMBL22791691 | 0.76 | ALDH1A1 (0.42) | GPR84HTR2AALDH1A1IMPDH2HTT | |
| SCHEMBL13548601 | 0.76 | KDM4E (0.48) | GPR84HTR2AALDH1A1IMPDH2HTT | |
| SCHEMBL13806393 | 0.74 | GPR84 (0.55) | GPR84HTR2AALDH1A1IMPDH2HTT | |
| SCHEMBL31123023 | 0.74 | GPR84 (0.55) | GPR84HTR2AALDH1A1IMPDH2HTT | |
| SCHEMBL10322780 | 0.74 | GPR84 (0.55) | GPR84HTR2AALDH1A1IMPDH2HTT | |
| SCHEMBL646254 | 0.74 | GPR84 (0.55) | GPR84HTR2AALDH1A1IMPDH2HTT | |
| SCHEMBL1891947 | 0.74 | GPR84 (0.55) | GPR84HTR2AALDH1A1IMPDH2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3107902-B1 | COMPOUNDS AND METHODS FOR INHIBITING FASCIN | CORNELL UNIV CORNELL CENTER FOR TECHNOLOGY ENTERPRISE & COMMERCIALIZATION CCTEC (US) | 2021-04-07 | — | — | EP | disclosed |
| WO-2019104067-A1 | CO-THERAPIES INCLUDING A METASTASIS INHIBITOR | CORNELL UNIVERSITY (US) | 2019-05-31 | — | — | WO | disclosed |
| CN-106397377-A | Electron-rich five-membered heterocyclic acid and method for decarboxylation and fluorination of derivative thereof | 中南大学 | 2017-02-15 | — | — | CN | disclosed |