SCHEMBL13549

SCHEMBL13549

c1cc2cnoc2cn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30140932 0.81
SCHEMBL13408 0.81
Benzo[D]Isoxazole SCHEMBL1355530 0.70
Benzo[D]Isoxazole SCHEMBL29366929 0.70
Benzo[D]Isoxazole SCHEMBL8438 0.70
Benzo[D]Isoxazole SCHEMBL28482344 0.68 TDO2 (0.39)
Benzo[D]Isoxazole SCHEMBL29184280 0.68 TDO2 (0.34)
Benzo[D]Isoxazole SCHEMBL21596877 0.68 TDO2 (0.34)
Benzo[D]Isoxazole SCHEMBL27335759 0.68 TDO2 (0.34)
Benzo[D]Isoxazole SCHEMBL1982876 0.68 TDO2 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 574 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113679717-B Methods for inhibiting fascin 康奈尔大学 2026-05-22 CN disclosed
US-20260124177-A1 CO-THERAPIES INCLUDING A METASTASIS INHIBITOR NOVITA PHARMACEUTICALS, INC. (US) 2026-05-07 US disclosed
EP-4735420-A1 ARYL INDOL-3-YL KETONE AND ARYL INDAZOL-3-YL KETONE INHIBITORS OF KIF18A Volastra Therapeutics, Inc. (US) 2026-05-06 EP disclosed
EP-4727548-A1 METHOD OF TREATING CANCER WITH INDOLINE INHIBITORS OF KIF18A Volastra Therapeutics, Inc. (US) 2026-04-22 EP disclosed
US-20260098018-A1 BICYCLIC 1,4-DIAZEPANONES AND THERAPEUTIC USES THEREOF CYTOKINETICS INC (US) 2026-04-09 US disclosed
US-12508245-B2 Co-therapies including a metastasis inhibitor NOVITA PHARMACEUTICALS, INC. (US) 2025-12-30 US disclosed
US-20250368654-A1 HETEROCYCLIC INHIBITORS OF ENPP1 VOLASTRA THERAPEUTICS, INC. (US) 2025-12-04 US disclosed
US-20250368657-A1 METHODS FOR INHIBITING FASCIN NOVITA PHARMACEUTICALS INC (US) 2025-12-04 US disclosed
EP-4646401-A1 NOVEL IONIZABLE LIPID COMPOUNDS FOR NUCLEIC ACID DELIVERY CELON PHARMA S.A. (PL) 2025-11-12 EP disclosed
US-20250333411-A1 COMPOUNDS AND METHODS FOR INHIBITING FASCIN CORNELL UNIVERSITY (US) 2025-10-30 US disclosed
US-6825201-B2 ANTIVIRAL ACTIVITY; TREATMENT OF HIV AND AIDS BRISTOL-MYERS SQUIBB COMPANY 2004-11-30 US disclosed
EP-1381366-A2 INDOLE, AZAINDOLE AND RELATED HETEROCYCLIC AMIDOPIPERAZINE DERIVATIVES BRISTOL-MYERS SQUIBB COMPANY (US) 2004-01-21 EP disclosed
US-20030096825-A1 Indole, azaindole and related heterocyclic amidopiperazine derivatives VIIV HEALTHCARE UK (NO. 5) LIMITED (GB) 2003-05-22 US disclosed
WO-2002085301-A2 INDOLE, AZAINDOLE AND RELATED HETEROCYCLIC AMIDOPIPERAZINE DERIVATIVES BRISTOL-MYERS SQUIBB COMPANY (US) 2002-10-31 WO disclosed
EP-0835242-A1 THIOAMIDES S-OXIDES FOR USE AS PESTICIDES Novartis AG (CH) 1998-04-15 EP disclosed
WO-1997000859-A1 THIOAMIDES S-OXIDES FOR USE AS PESTICIDES NOVARTIS AG (CH) 1997-01-09 WO disclosed
EP-0000338-B1 ISOXAZOLO(5,4-C)PYRIDINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM H.Lundbeck &amp; Co., A/S (DK) 1981-11-25 EP disclosed
EP-0027279-A1 Isoxazolo(5,4-C)pyridines H.Lundbeck &amp; Co., A/S (DK) 1981-04-22 EP disclosed
EP-0000338-A2 Isoxazolo(5,4-c)pyridine derivatives, their preparation and pharmaceutical compositions containing them H.Lundbeck &amp; Co., A/S (DK) 1979-01-24 EP disclosed
EP-0000338-A2 Isoxazolo(5,4-c)pyridine derivatives, their preparation and pharmaceutical compositions containing them H.Lundbeck &amp; Co., A/S (DK) 1979-01-24 EP disclosed