SCHEMBL30140932

SCHEMBL30140932

c1cc2oncc2cn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13408 1.00
SCHEMBL13549 0.81
Benzo[D]Isoxazole SCHEMBL29366929 0.70
Benzo[D]Isoxazole SCHEMBL1355530 0.70
Benzo[D]Isoxazole SCHEMBL8438 0.70
Benzo[D]Isoxazole SCHEMBL5778868 0.68 TDO2 (0.34)
Benzo[D]Isoxazole SCHEMBL28482344 0.68 TDO2 (0.39)
Benzo[D]Isoxazole SCHEMBL29184280 0.68 TDO2 (0.34)
Benzo[D]Isoxazole SCHEMBL21596877 0.68 TDO2 (0.34)
Benzo[D]Isoxazole SCHEMBL5158032 0.68 TDO2 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119768392-A Aryl or heteroaryl substituted glutarimide derivatives and uses thereof 标新生物医药科技(上海)有限公司 2025-04-04 CN claimed
CN-119654316-A Thioglutarimide isoindolinone skeleton-based compound and application thereof 标新生物医药科技(上海)有限公司 2025-03-18 CN claimed
CN-119451952-A Oxo-isoindolinyl substituted tetrahydropyrimidinedione derivative and application thereof 标新生物医药科技(上海)有限公司 2025-02-14 CN claimed
CN-122071471-A Heterocyclic compounds 武田药品工业株式会社 2026-05-22 CN disclosed
CN-113679717-B Methods for inhibiting fascin 康奈尔大学 2026-05-22 CN disclosed
CN-122010946-A Heterocyclic compounds 武田药品工业株式会社 2026-05-12 CN disclosed
CN-122010945-A Heterocyclic compounds 武田药品工业株式会社 2026-05-12 CN disclosed
EP-4646401-A1 NOVEL IONIZABLE LIPID COMPOUNDS FOR NUCLEIC ACID DELIVERY CELON PHARMA S.A. (PL) 2025-11-12 EP disclosed
CN-115843295-B NAMPT modulators 赛特凯恩蒂克公司 2025-04-15 CN disclosed
CN-119768392-A Aryl or heteroaryl substituted glutarimide derivatives and uses thereof 标新生物医药科技(上海)有限公司 2025-04-04 CN disclosed
CN-119654316-A Thioglutarimide isoindolinone skeleton-based compound and application thereof 标新生物医药科技(上海)有限公司 2025-03-18 CN disclosed
CN-111757875-B Dihydrobenzofuran and indene analogs as myocardial segment inhibitors 赛特凯恩蒂克公司 2024-01-09 CN disclosed
US-20230382889-A1 COMPOUNDS FOR INHIBITING KIF18A VOLASTRA THERAPEUTICS, INC. (US) 2023-11-30 US disclosed
CN-116655618-A Probes for imaging huntingtin CHDI基金会股份有限公司 2023-08-29 CN disclosed
CN-116635378-A Bicyclic 1, 4-diazacycloheptanones and therapeutic uses thereof 赛特凯恩蒂克公司 2023-08-22 CN disclosed
CN-111349087-B Compounds and methods for inhibiting fascin 康奈尔大学 2023-07-14 CN disclosed
CN-107108534-B Probes for imaging huntingtin CHDI基金会股份有限公司 2023-05-09 CN disclosed
CN-115996912-A Iminothiolanone inhibitors of ENPP1 沃拉斯查疗法公司 2023-04-21 CN disclosed
CN-115843295-A NAMPT modulators 赛特凯恩蒂克公司 2023-03-24 CN disclosed
CN-115515934-A NAMPT modulators 赛特凯恩蒂克公司 2022-12-23 CN disclosed