SCHEMBL135491

SCHEMBL135491

CCCCCCCCCCCCCCOC(=O)c1cccnc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 1.00
L3MBTL1 Q9Y468 1/20 0.89
MAPT P10636 4/20 0.81
ALDH1A1 P00352 4/20 0.81
KMT2A Q03164 2/20 0.81
MEN1 O00255 1/20 0.81
HPGD P15428 1/20 0.81
NFKB1 P19838 2/20 0.70
NFKB2 Q00653 2/20 0.70
RELA Q04206 2/20 0.70
NPC1 O15118 2/20 0.70
POLB P06746 1/20 0.70
SMN1; SMN2 Q16637 1/20 0.70
TSHR P16473 3/20 0.63
CYP1A2 P05177 1/20 0.63
CYP2C9 P11712 1/20 0.63
CYP2C19 P33261 1/20 0.63
RAB9A P51151 1/20 0.56
TDP1 Q9NUW8 1/20 0.55
TP53 P04637 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3402747 1.00 LMNA (1.00) LMNAL3MBTL1MAPTALDH1A1KMT2A
SCHEMBL6799776 1.00 LMNA (1.00) LMNAL3MBTL1MAPTALDH1A1KMT2A
SCHEMBL2939266 1.00 LMNA (1.00) LMNAL3MBTL1MAPTALDH1A1KMT2A
SCHEMBL10460555 1.00 LMNA (1.00) LMNAL3MBTL1MAPTALDH1A1KMT2A
SCHEMBL22092312 1.00 LMNA (1.00) LMNAL3MBTL1MAPTALDH1A1KMT2A
SCHEMBL285214 1.00 LMNA (1.00) LMNAL3MBTL1MAPTALDH1A1KMT2A
SCHEMBL9717064 1.00 LMNA (1.00) LMNAL3MBTL1MAPTALDH1A1KMT2A
SCHEMBL4275232 1.00 LMNA (1.00) LMNAL3MBTL1MAPTALDH1A1KMT2A
SCHEMBL589021 1.00 LMNA (1.00) LMNAL3MBTL1MAPTALDH1A1KMT2A
SCHEMBL9717062 1.00 LMNA (1.00) LMNAL3MBTL1MAPTALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 547 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119925231-A Composition for improving anti-aging and tightening effects and preparation method thereof 广州西米尔生物科技有限公司 2025-05-06 CN claimed
CN-117777016-A Synthesis method of myristyl alcohol nicotinate 上海克琴科技有限公司 2024-03-29 CN claimed
CN-117100629-A Terpene plastid for cosmetics and preparation method thereof 浙江睿颜新材料科技有限公司 2023-11-24 CN claimed
CN-116687793-A Use of myristyl nicotinate in cosmetics 杭州睿研前瞻生物科技有限公司 2023-09-05 CN claimed
CN-111956561-A Lip cosmetic and preparation method thereof 陈姝君 2020-11-20 CN claimed
EP-1898867-B1 METHOD FOR TREATING HAIR GROWTH DISORDERS, SUCH AS FEMALE PATTERN ALOPECIA, AND COMPOSITIONS USEFUL THEREFORE ARIZONA BOARD OF REGENTS ACTING ON BEHALF OF THE UNIV OF ARIZONA (US) 2017-08-09 EP claimed
US-9642845-B2 Method for alleviating side effects of retinoic acid therapy and/or improving efficacy without interfering with efficacy UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2017-05-09 US claimed
CN-103127111-B Be used for the treatment of the method for natural on-off cycles of hair growth disease such as female pattern alopecia and can be used for this compositions THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2016-02-10 CN claimed
US-8790626-B2 Method for treating hair growth disorders, such as female pattern alopecia, and compositions useful therefore THE UNIVERSITY OF KENTUCKY (US) 2014-07-29 US claimed
EP-2120917-B1 Method for alleviating side effects of retinoic acid therapy and/or improving efficacy without interfering with efficacy UNIV KENTUCKY RES FOUND (US) 2014-01-22 EP claimed
US-8114390-B2 Method for treating hair growth disorders, such as female pattern alopecia, and compositions useful therefore THE UNIVERSITY OF KENTUCKY (US) 2012-02-14 US claimed
US-20100173957-A1 METHOD FOR ALLEVIATING SIDE EFFECTS OF RETINOIC ACID THERAPY AND/OR IMPROVING EFFICACY WITHOUT INTERFERING WITH EFFICACY NIADYNE, INC. 2010-07-08 US claimed
JP-2010520202-A 2010-06-10 JP claimed
US-20090318508-A1 Method for Treating Hair Growth Disorders, Such as Female Pattern Alopecia, and Compositions Useful Therefore NIADYNE, INC. 2009-12-24 US claimed
EP-2120917-A2 METHOD FOR ALLEVIATING SIDE EFFECTS OF RETINOIC ACID THERAPY AND/OR IMPROVING EFFICACY WITHOUT INTERFERING WITH EFFICACY University Of Kentucky Research Foundation (US) 2009-11-25 EP claimed
CN-101355986-A Methods for treating hair growth disorders such as female pattern alopecia and compositions useful therefor ARIZON BOARD OF REGENTS ON BEH (US) 2009-01-28 CN claimed
WO-2008106177-A2 METHOD FOR ALLEVIATING SIDE EFFECTS OF RETINOIC ACID THERAPY AND/OR IMPROVING EFFICACY WITHOUT INTERFERING WITH EFFICACY UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2008-09-04 WO claimed
EP-1898867-A1 METHOD FOR TREATING HAIR GROWTH DISORDERS, SUCH AS FEMALE PATTERN ALOPECIA, AND COMPOSITIONS USEFUL THEREFORE Arizona Board of Regents, on behalf of the University of Arizona (US) 2008-03-19 EP claimed
WO-2007002640-A1 METHOD FOR TREATING HAIR GROWTH DISORDERS, SUCH AS FEMALE PATTERN ALOPECIA, AND COMPOSITIONS USEFUL THEREFORE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2007-01-04 WO claimed
US-6677361-B2 OR NICOTINIC ACID ESTERS UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION 2004-01-13 US claimed