SCHEMBL4275232

SCHEMBL4275232

CCCCCCCCCCCCCCCCCCCCCCCCCCCCOC(=O)c1cccnc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 1.00
L3MBTL1 Q9Y468 1/20 0.89
MAPT P10636 4/20 0.81
ALDH1A1 P00352 4/20 0.81
KMT2A Q03164 2/20 0.81
MEN1 O00255 1/20 0.81
HPGD P15428 1/20 0.81
NFKB1 P19838 2/20 0.70
NFKB2 Q00653 2/20 0.70
RELA Q04206 2/20 0.70
NPC1 O15118 2/20 0.70
POLB P06746 1/20 0.70
SMN1; SMN2 Q16637 1/20 0.70
TSHR P16473 3/20 0.63
CYP1A2 P05177 1/20 0.63
CYP2C9 P11712 1/20 0.63
CYP2C19 P33261 1/20 0.63
RAB9A P51151 1/20 0.56
TDP1 Q9NUW8 1/20 0.55
TP53 P04637 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3402747 1.00 LMNA (1.00) LMNAL3MBTL1MAPTALDH1A1KMT2A
SCHEMBL6799776 1.00 LMNA (1.00) LMNAL3MBTL1MAPTALDH1A1KMT2A
SCHEMBL135491 1.00 LMNA (1.00) LMNAL3MBTL1MAPTALDH1A1KMT2A
SCHEMBL2939266 1.00 LMNA (1.00) LMNAL3MBTL1MAPTALDH1A1KMT2A
SCHEMBL10460555 1.00 LMNA (1.00) LMNAL3MBTL1MAPTALDH1A1KMT2A
SCHEMBL22092312 1.00 LMNA (1.00) LMNAL3MBTL1MAPTALDH1A1KMT2A
SCHEMBL285214 1.00 LMNA (1.00) LMNAL3MBTL1MAPTALDH1A1KMT2A
SCHEMBL9717064 1.00 LMNA (1.00) LMNAL3MBTL1MAPTALDH1A1KMT2A
SCHEMBL589021 1.00 LMNA (1.00) LMNAL3MBTL1MAPTALDH1A1KMT2A
SCHEMBL9717062 1.00 LMNA (1.00) LMNAL3MBTL1MAPTALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7615641-B2 Long chain aliphatic alcohol derivatives and methods of making and using same SINO PHARMACEUTICALS CORPORATION (CA) 2009-11-10 US claimed
US-20060020135-A1 Long chain aliphatic alcohol derivatives and methods of making and using same SINO PHARMACEUTICALS CORPORATION (CA) 2006-01-26 US claimed
US-7615641-B2 Long chain aliphatic alcohol derivatives and methods of making and using same SINO PHARMACEUTICALS CORPORATION (CA) 2009-11-10 US disclosed
US-7615641-B2 Long chain aliphatic alcohol derivatives and methods of making and using same SINO PHARMACEUTICALS CORPORATION (CA) 2009-11-10 US disclosed
US-7615641-B2 Long chain aliphatic alcohol derivatives and methods of making and using same SINO PHARMACEUTICALS CORPORATION (CA) 2009-11-10 US disclosed
US-7615641-B2 Long chain aliphatic alcohol derivatives and methods of making and using same SINO PHARMACEUTICALS CORPORATION (CA) 2009-11-10 US disclosed
US-20060020135-A1 Long chain aliphatic alcohol derivatives and methods of making and using same SINO PHARMACEUTICALS CORPORATION (CA) 2006-01-26 US disclosed
US-20060020135-A1 Long chain aliphatic alcohol derivatives and methods of making and using same SINO PHARMACEUTICALS CORPORATION (CA) 2006-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060020135-A1 Long chain aliphatic alcohol derivatives and methods of making and using same ADH1C, ADH5, NAPRT LMNA 925/4885L3MBTL1 3861/4885MAPT 3158/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.