Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.89 |
| ▸ | MAPT | P10636 | 4/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.81 |
| ▸ | MEN1 | O00255 | 1/20 | 0.81 |
| ▸ | HPGD | P15428 | 1/20 | 0.81 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.70 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.70 |
| ▸ | RELA | Q04206 | 2/20 | 0.70 |
| ▸ | NPC1 | O15118 | 2/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 3/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3402747 | 1.00 | LMNA (1.00) | LMNAL3MBTL1MAPTALDH1A1KMT2A | |
| SCHEMBL6799776 | 1.00 | LMNA (1.00) | LMNAL3MBTL1MAPTALDH1A1KMT2A | |
| SCHEMBL135491 | 1.00 | LMNA (1.00) | LMNAL3MBTL1MAPTALDH1A1KMT2A | |
| SCHEMBL2939266 | 1.00 | LMNA (1.00) | LMNAL3MBTL1MAPTALDH1A1KMT2A | |
| SCHEMBL10460555 | 1.00 | LMNA (1.00) | LMNAL3MBTL1MAPTALDH1A1KMT2A | |
| SCHEMBL22092312 | 1.00 | LMNA (1.00) | LMNAL3MBTL1MAPTALDH1A1KMT2A | |
| SCHEMBL285214 | 1.00 | LMNA (1.00) | LMNAL3MBTL1MAPTALDH1A1KMT2A | |
| SCHEMBL9717064 | 1.00 | LMNA (1.00) | LMNAL3MBTL1MAPTALDH1A1KMT2A | |
| SCHEMBL4275232 | 1.00 | LMNA (1.00) | LMNAL3MBTL1MAPTALDH1A1KMT2A | |
| SCHEMBL589021 | 1.00 | LMNA (1.00) | LMNAL3MBTL1MAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3322419-B1 | SYNTHESES, ACTIVITIES, AND METHODS OF USE OF DIHYDRONICOTINAMIDE RIBOSIDE DERIVATIVES | UNIV CORNELL (US) | 2025-09-03 | — | — | EP | disclosed |
| US-11926644-B2 | Syntheses, activities, and methods of use of dihydronicotinamide riboside derivatives | CORNELL UNIVERSITY (US) | 2024-03-12 | — | — | US | disclosed |
| CN-110709406-B | Beta-nicotinate nucleotide and preparation method thereof | 康奈尔大学 | 2022-11-08 | — | — | CN | disclosed |
| CN-109705120-A | Imidazole simultaneously [1,2-a] pyridine compounds and its preparation method and application | 广东药科大学 | 2019-05-03 | — | — | CN | disclosed |
| EP-0489581-A2 | Cosmetic composition | UNILEVER PLC (GB) | 1992-06-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11926644-B2 | Syntheses, activities, and methods of use of dihydronicotinamide riboside derivatives | NQO1, NME4, NQO2 | LMNA 1331/4885L3MBTL1 3044/4885MAPT 1796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.