SCHEMBL6799776

SCHEMBL6799776

CCCCCCCCCCOC(=O)c1cccnc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 1.00
L3MBTL1 Q9Y468 1/20 0.89
MAPT P10636 4/20 0.81
ALDH1A1 P00352 4/20 0.81
KMT2A Q03164 2/20 0.81
MEN1 O00255 1/20 0.81
HPGD P15428 1/20 0.81
NFKB1 P19838 2/20 0.70
NFKB2 Q00653 2/20 0.70
RELA Q04206 2/20 0.70
NPC1 O15118 2/20 0.70
POLB P06746 1/20 0.70
SMN1; SMN2 Q16637 1/20 0.70
TSHR P16473 3/20 0.63
CYP1A2 P05177 1/20 0.63
CYP2C9 P11712 1/20 0.63
CYP2C19 P33261 1/20 0.63
RAB9A P51151 1/20 0.56
TDP1 Q9NUW8 1/20 0.55
TP53 P04637 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3402747 1.00 LMNA (1.00) LMNAL3MBTL1MAPTALDH1A1KMT2A
SCHEMBL135491 1.00 LMNA (1.00) LMNAL3MBTL1MAPTALDH1A1KMT2A
SCHEMBL2939266 1.00 LMNA (1.00) LMNAL3MBTL1MAPTALDH1A1KMT2A
SCHEMBL10460555 1.00 LMNA (1.00) LMNAL3MBTL1MAPTALDH1A1KMT2A
SCHEMBL22092312 1.00 LMNA (1.00) LMNAL3MBTL1MAPTALDH1A1KMT2A
SCHEMBL285214 1.00 LMNA (1.00) LMNAL3MBTL1MAPTALDH1A1KMT2A
SCHEMBL9717064 1.00 LMNA (1.00) LMNAL3MBTL1MAPTALDH1A1KMT2A
SCHEMBL4275232 1.00 LMNA (1.00) LMNAL3MBTL1MAPTALDH1A1KMT2A
SCHEMBL589021 1.00 LMNA (1.00) LMNAL3MBTL1MAPTALDH1A1KMT2A
SCHEMBL9717062 1.00 LMNA (1.00) LMNAL3MBTL1MAPTALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040081672-A1 Niacinamide, niacin, and niacin esters based delivery systems for treating topical disorders of skin and skin aging GUPTA SHYAM K (US) 2004-04-29 US claimed
EP-0576622-B1 LITHOGRAPHIC PRINTING PLATES EASTMAN KODAK CO (US) 1997-11-05 EP claimed
CN-122031446-A External pharmaceutical composition containing loxoprofen and felbinac 第一三共健康事业株式会社 2026-05-15 CN disclosed
CN-122031445-A External pharmaceutical composition containing loxoprofen 第一三共健康事业株式会社 2026-05-15 CN disclosed
CN-122031449-A External pharmaceutical composition containing loxoprofen and diclofenac 第一三共健康事业株式会社 2026-05-15 CN disclosed
CN-113574055-A PCSK9 inhibitors and methods of use thereof 阿斯利康(瑞典)有限公司 2021-10-29 CN disclosed
CN-109310661-B Blood flow improving agent, royal jelly composition, and method for producing royal jelly composition 株式会社山田养蜂场本社 2021-06-04 CN disclosed
CN-111939125-A Self-emulsifying compositions of omega-3 fatty acids 持田制药株式会社 2020-11-17 CN disclosed
CN-111888343-A Self-emulsifying compositions of omega-3 fatty acids 持田制药株式会社 2020-11-06 CN disclosed
CN-110840874-A Self-emulsifying compositions of omega-3 fatty acids 持田制药株式会社 2020-02-28 CN disclosed
EP-0489581-A2 Cosmetic composition UNILEVER PLC (GB) 1992-06-10 EP disclosed