SCHEMBL1355428

SCHEMBL1355428

CC(C)Cc1cc(C(=O)O)cc(C(=O)O)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 4/20 0.46
PTGS2 P35354 4/20 0.46
LMNA P02545 2/20 0.46
CYP2C9 P11712 2/20 0.46
AKR1C3 P42330 2/20 0.46
CXCR1 P25024 2/20 0.46
CXCR2 P25025 2/20 0.46
AKR1C2 P52895 2/20 0.46
ALB P02768 1/20 0.46
ESR1 P03372 1/20 0.46
ALOX5 P09917 1/20 0.46
RARB P10826 1/20 0.46
ADRB3 P13945 1/20 0.46
NFKB1 P19838 1/20 0.46
HTR2A P28223 1/20 0.46
NR1I3 Q14994 1/20 0.46
SLC22A6 Q4U2R8 1/20 0.46
CXCL8 P10145 1/20 0.46
TSHR P16473 1/20 0.46
BLM P54132 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16653943 0.96 PTGS1 (0.46) PTGS1PTGS2LMNACYP2C9AKR1C3
SCHEMBL17756315 0.88 TPMT (0.57) PTGS1PTGS2LMNACYP2C9AKR1C3
SCHEMBL15520375 0.88 CA12 (0.54) PTGS1PTGS2LMNACYP2C9AKR1C3
SCHEMBL2723874 0.87 TPMT (0.41) PTGS1PTGS2LMNACYP2C9AKR1C3
SCHEMBL27630008 0.83 FBP1 (0.39) PTGS1PTGS2LMNACYP2C9AKR1C3
SCHEMBL11989139 0.83 LMNA (0.44) PTGS1PTGS2LMNACYP2C9AKR1C3
SCHEMBL16952003 0.82 CREBBP (0.40) PTGS1PTGS2LMNACYP2C9AKR1C3
SCHEMBL16952005 0.82 FBP1 (0.40) PTGS1PTGS2LMNACYP2C9AKR1C3
SCHEMBL2668266 0.82 KMT2A (0.50) RARBCREBBPALDH1A1GRIN2DGRIN2A
SCHEMBL27829547 0.82 MAPT (0.45) TPMTALDH1A1FOLH1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12576386-B2 Aluminum-based metal-organic framework having three dimensional porous structure and comprising at least two types of ligands, preparation method therefor, and use thereof KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2026-03-17 US claimed
US-20220323931-A1 NOVEL ALUMINUM-BASED METAL-ORGANIC FRAMEWORK HAVING THREE DIMENSIONAL POROUS STRUCTURE AND COMPRISING AT LEAST TWO TYPES OF LIGANDS, PREPARATION METHOD THEREFOR, AND USE THEREOF KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2022-10-13 US claimed
EP-4023656-A1 NOVEL ALUMINUM-BASED METAL-ORGANIC FRAMEWORK HAVING THREE DIMENSIONAL POROUS STRUCTURE AND COMPRISING AT LEAST TWO TYPES OF LIGANDS, PREPARATION METHOD THEREFOR, AND USE THEREOF Korea Research Institute of Chemical Technology (KR) 2022-07-06 EP claimed
WO-2021040455-A1 NOVEL ALUMINUM-BASED METAL-ORGANIC FRAMEWORK HAVING THREE DIMENSIONAL POROUS STRUCTURE AND COMPRISING AT LEAST TWO TYPES OF LIGANDS, PREPARATION METHOD THEREFOR, AND USE THEREOF 한국화학연구원 2021-03-04 WO claimed
US-12576386-B2 Aluminum-based metal-organic framework having three dimensional porous structure and comprising at least two types of ligands, preparation method therefor, and use thereof KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2026-03-17 US disclosed
US-20220323931-A1 NOVEL ALUMINUM-BASED METAL-ORGANIC FRAMEWORK HAVING THREE DIMENSIONAL POROUS STRUCTURE AND COMPRISING AT LEAST TWO TYPES OF LIGANDS, PREPARATION METHOD THEREFOR, AND USE THEREOF KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2022-10-13 US disclosed
CN-111138852-B Polyamide compound for improving laser weldability 上海金发科技发展有限公司 2022-07-08 CN disclosed
EP-4023656-A1 NOVEL ALUMINUM-BASED METAL-ORGANIC FRAMEWORK HAVING THREE DIMENSIONAL POROUS STRUCTURE AND COMPRISING AT LEAST TWO TYPES OF LIGANDS, PREPARATION METHOD THEREFOR, AND USE THEREOF Korea Research Institute of Chemical Technology (KR) 2022-07-06 EP disclosed
EP-3230339-B1 EPOXY RESIN COMPOSITION, PREPREG, FIBER-REINFORCED PLASTIC MATERIAL, AND MANUFACTURING METHOD FOR FIBER-REINFORCED PLASTIC MATERIAL TORAY INDUSTRIES (JP) 2022-03-23 EP disclosed
WO-2021129503-A1 POLYAMIDE COMPOSITE FOR IMPROVING LASER WELDABILITY 上海金发科技发展有限公司 2021-07-01 WO disclosed
WO-2021040455-A1 NOVEL ALUMINUM-BASED METAL-ORGANIC FRAMEWORK HAVING THREE DIMENSIONAL POROUS STRUCTURE AND COMPRISING AT LEAST TWO TYPES OF LIGANDS, PREPARATION METHOD THEREFOR, AND USE THEREOF 한국화학연구원 2021-03-04 WO disclosed
CN-112375376-A Polyamide composition suitable for liquid-assisted molding and preparation method thereof 上海金发科技发展有限公司 2021-02-19 CN disclosed
EP-2192139-A1 INCLUSION COMPLEX CONTAINING EPOXY RESIN COMPOSITION FOR SEMICONDUCTOR ENCAPSULATION Nippon Soda Co., Ltd. (JP) 2010-06-02 EP disclosed
US-20080227946-A1 Thermosetting Composition and Curing Method Thereof SHOWA DENKO K.K. 2008-09-18 US disclosed
EP-1732980-A1 THERMOSETTING COMPOSITION AND CURING METHOD THEREOF SHOWA DENKO KABUSHIKI KAISHA (JP) 2006-12-20 EP disclosed
US-20060257727-A1 Reactive polymer-supporting porous film for battery seperator and use thereof NITTO DENKO CORPORATION (JP) 2006-11-16 US disclosed
EP-1667253-A1 REACTIVE POLYMER-SUPPORTING POROUS FILM FOR BATTERY SEPARATOR AND USE THEREOF NITTO DENKO CORPORATION (JP) 2006-06-07 EP disclosed
WO-2005097882-A1 THERMOSETTING COMPOSITION AND CURING METHOD THEREOF SHOWA DENKO K.K. (JP) 2005-10-20 WO disclosed
US-4613678-A NITROGEN CONTAINING CATALYST THE DOW CHEMICAL COMPANY (US) 1986-09-23 US disclosed
US-4347351-A ESTERIFICATION FOLLOWED BY POLYCONDENSATION THE DOW CHEMICAL COMPANY (US) 1982-08-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12576386-B2 Aluminum-based metal-organic framework having three dimensional porous structure and comprising at least two types of ligands, preparation method therefor, and use thereof ALAD, SLC38A7, SLC5A11 PTGS1 260/4885PTGS2 303/4885LMNA 2218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.