Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.37 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16958657 | 0.83 | SLC7A5 (0.45) | LMNACXCR1CXCR2NFKB1ALDH1A1 | |
| SCHEMBL16653943 | 0.82 | PTGS1 (0.46) | CREBBPFBP1PTGS1PTGS2LMNA | |
| SCHEMBL1355428 | 0.82 | PTGS1 (0.46) | CREBBPFBP1PTGS1PTGS2LMNA | |
| SCHEMBL16956242 | 0.80 | GABRA1 (0.35) | PTGS1PTGS2LMNACYP2C9AKR1C3 | |
| SCHEMBL15520375 | 0.76 | CA12 (0.54) | CREBBPFBP1PTGS1PTGS2LMNA | |
| SCHEMBL17756315 | 0.76 | TPMT (0.57) | CREBBPFBP1PTGS1PTGS2LMNA | |
| SCHEMBL2723874 | 0.75 | TPMT (0.41) | CREBBPFBP1PTGS1PTGS2LMNA | |
| SCHEMBL16952005 | 0.74 | FBP1 (0.40) | CREBBPFBP1PTGS1PTGS2LMNA | |
| SCHEMBL16952636 | 0.74 | GABRA1 (0.35) | — | |
| SCHEMBL16951018 | 0.74 | OPRM1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |