Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 8/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PI4KA | P42356 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16705355 | 0.78 | CYP1A2 (0.40) | PDE10AMTNR1AMTNR1BPIK3CAPIK3CD | |
| SCHEMBL15942810 | 0.77 | CYP1A2 (0.44) | CSF1RPDE10APDGFRBPDGFRAPIK3CA | |
| SCHEMBL622678 | 0.77 | PDGFRB (0.48) | CSF1RPDE10APDGFRBPDGFRAHPGD | |
| SCHEMBL13552130 | 0.77 | HTT (0.41) | CSF1RPDE10AMTNR1AMTNR1BPDGFRB | |
| SCHEMBL25113003 | 0.76 | EGFR (0.41) | CSF1RPDE10APDGFRBPDGFRAPIK3CA | |
| SCHEMBL622358 | 0.76 | HPGD (0.41) | CSF1RPDE10AMTNR1AMTNR1BPDGFRB | |
| SCHEMBL21746277 | 0.76 | ALDH1A1 (0.43) | HPGDNPC1RAB9A | |
| SCHEMBL622192 | 0.76 | PIK3CA (0.42) | CSF1RPDE10APDGFRBPDGFRAPIK3CA | |
| SCHEMBL19808389 | 0.76 | CYP1A2 (0.46) | PDE10AMTNR1AMTNR1BHPGDNPC1 | |
| SCHEMBL17244314 | 0.76 | PDGFRB (0.40) | CSF1RPDE10APDGFRBPDGFRAPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120270893-A1 | SUBSTITUTED ACETYL-COA CARBOXYLASE INHIBITORS | PFIZER INC. (US) | 2012-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120270893-A1 | SUBSTITUTED ACETYL-COA CARBOXYLASE INHIBITORS | ACACA, ACACB, ACAT1 | CSF1R 2743/4885PDE10A 3233/4885MTNR1A 2244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.