SCHEMBL13555451

SCHEMBL13555451

Cc1nc2c(-c3ccccc3)c3nsnc3c(-c3ccccc3)c2nc1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 2/20 0.40
CHEK1 O14757 1/20 0.40
AKT2 P31751 1/20 0.40
BRD2 P25440 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.39
TP53 P04637 2/20 0.39
TDO2 P48775 1/20 0.38
MAPT P10636 5/20 0.37
SMN1; SMN2 Q16637 4/20 0.36
NPC1 O15118 3/20 0.36
RAB9A P51151 3/20 0.36
KDM4E B2RXH2 3/20 0.36
HTT P42858 2/20 0.36
ALDH1A1 P00352 2/20 0.36
LMNA P02545 2/20 0.36
HPGD P15428 2/20 0.36
GAA P10253 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
ADRA2A P08913 1/20 0.36
ADORA2A P29274 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13555449 0.85 ALDH1A1 (0.34) BRD4CHEK1AKT2BRD2L3MBTL1
SCHEMBL15086106 0.82 ESR1 (0.39) AKT2L3MBTL1MAPTRAB9AKDM4E
SCHEMBL13555444 0.82 DHFR (0.41) AKT2L3MBTL1TP53MAPTSMN1; SMN2
SCHEMBL13228950 0.82 AKT2 (0.39) BRD4CHEK1AKT2BRD2L3MBTL1
SCHEMBL14701343 0.79 ESR1 (0.36) L3MBTL1MAPTSMN1; SMN2KDM4EHTT
SCHEMBL21202691 0.79 ALDH1A1 (0.39) AKT2L3MBTL1TP53MAPTSMN1; SMN2
SCHEMBL14515092 0.78 AKT2 (0.37) BRD4CHEK1AKT2BRD2TDO2
SCHEMBL19104394 0.77 BRD4 (0.48) BRD4CHEK1AKT2BRD2L3MBTL1
SCHEMBL15672183 0.76 MEN1 (0.33) L3MBTL1MAPTRAB9AKDM4EALDH1A1
SCHEMBL19104413 0.76 PDPK1 (0.36) TDO2MAPTSMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10367148-B2 Light-emitting device, electronic apparatus, and inspection method SEIKO EPSON CORPORATION (JP) 2019-07-30 US disclosed
US-9876177-B2 Thiadiazole-based compound, light emitting element compound, light emitting element, light emitting device, authentication device, and electronic device SEIKO EPSON CORPORATION (JP) 2018-01-23 US disclosed
US-9876177-B2 Thiadiazole-based compound, light emitting element compound, light emitting element, light emitting device, authentication device, and electronic device SEIKO EPSON CORPORATION (JP) 2018-01-23 US disclosed
US-20170365793-A1 THIADIAZOLE-BASED COMPOUND, LIGHT EMITTING ELEMENT COMPOUND, LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE, AUTHENTICATION DEVICE, AND ELECTRONIC DEVICE SEIKO EPSON CORP (JP) 2017-12-21 US disclosed
US-20170365793-A1 THIADIAZOLE-BASED COMPOUND, LIGHT EMITTING ELEMENT COMPOUND, LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE, AUTHENTICATION DEVICE, AND ELECTRONIC DEVICE SEIKO EPSON CORP (JP) 2017-12-21 US disclosed
US-9401460-B2 Light emitting element SEIKO EPSON CORPORATION (JP) 2016-07-26 US disclosed
US-9224928-B2 Light emitting element, light emitting device and electronic apparatus SEIKO EPSON CORPORATION (JP) 2015-12-29 US disclosed
US-9159932-B2 Light emitting element, light emitting device, and electronic device SEIKO EPSON CORPORATION (JP) 2015-10-13 US disclosed
US-20150236226-A1 LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE AND ELECTRONIC APPARATUS SEIKO EPSON CORP (JP) 2015-08-20 US disclosed
US-20140332835-A1 LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE AND ELECTRONIC APPARATUS SEIKO EPSON CORPORATION (JP) 2014-11-13 US disclosed
US-8803138-B2 Light emitting element, light emitting device and electronic apparatus SEIKO EPSON CORPORATION (JP) 2014-08-12 US disclosed
US-20130168654-A1 LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE AND ELECTRONIC APPARATUS SEIKO EPSON CORPORATION (JP) 2013-07-04 US disclosed
US-20130037785-A1 LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE, AND ELECTRONIC DEVICE SEIKO EPSON CORPORATION (JP) 2013-02-14 US disclosed
US-20120267615-A1 THIADIAZOLE-BASED COMPOUND, LIGHT EMITTING ELEMENT COMPOUND, LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE, AUTHENTICATION DEVICE, AND ELECTRONIC DEVICE SEIKO EPSON CORPORATION (JP) 2012-10-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10367148-B2 Light-emitting device, electronic apparatus, and inspection method CRY1, INF2, CRY2 BRD4 3448/4885CHEK1 3995/4885AKT2 4640/4885
US-20170365793-A1 THIADIAZOLE-BASED COMPOUND, LIGHT EMITTING ELEMENT COMPOUND, LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE, AUTHENTICATION DEVICE, AND ELECTRONIC DEVICE CYP2C19, CYP2C9, CYP1A2 BRD4 349/4885CHEK1 2883/4885AKT2 4630/4885
US-20120267615-A1 THIADIAZOLE-BASED COMPOUND, LIGHT EMITTING ELEMENT COMPOUND, LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE, AUTHENTICATION DEVICE, AND ELECTRONIC DEVICE CYP2C19, CYP2C9, AADAC BRD4 290/4885CHEK1 2935/4885AKT2 4656/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.