Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 3/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | CDC25A | P30304 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7009458 | 0.89 | ACE2 (0.58) | ACE2KDM4EGRM1MEN1CYP1A2 | |
| SCHEMBL6935737 | 0.88 | ACE2 (0.57) | ACE2KDM4EGRM1MEN1CYP1A2 | |
| SCHEMBL18309183 | 0.87 | ACE2 (0.53) | ACE2KDM4EMEN1KMT2ARXRA | |
| SCHEMBL21104802 | 0.85 | CDC25A (0.61) | ACE2KDM4ETDP1RXRAALDH1A1 | |
| SCHEMBL27558455 | 0.85 | ACE2 (0.54) | ACE2KDM4EGRM1MEN1CYP1A2 | |
| SCHEMBL7109111 | 0.85 | ACE2 (0.54) | ACE2KDM4EGRM1MEN1CYP1A2 | |
| SCHEMBL1356407 | 0.84 | ACE2 (0.67) | ACE2KDM4EGRM1MEN1CYP1A2 | |
| SCHEMBL2159198 | 0.84 | ACE2 (0.54) | ACE2KDM4EGRM1RXRARXRB | |
| SCHEMBL13816269 | 0.83 | ACE2 (0.61) | ACE2KDM4EGRM1MEN1CYP1A2 | |
| SCHEMBL8559784 | 0.83 | PLA2G2D (0.54) | ACE2KDM4EGRM1MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230051807-A1 | PORPHYRIN PHOTOSENSITIZER AND COBALOXIME COCATALYST AND METHODS OF USE THEREOF | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2023-02-16 | — | — | US | disclosed |
| EP-3230339-B1 | EPOXY RESIN COMPOSITION, PREPREG, FIBER-REINFORCED PLASTIC MATERIAL, AND MANUFACTURING METHOD FOR FIBER-REINFORCED PLASTIC MATERIAL | TORAY INDUSTRIES (JP) | 2022-03-23 | — | — | EP | disclosed |
| US-10201803-B2 | Polymer-metal organic framework materials and methods of using the same | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-02-12 | — | — | US | disclosed |
| US-20170362376-A1 | EPOXY RESIN COMPOSITION, PREPREG, FIBER-REINFORCED PLASTIC MATERIAL, AND MANUFACTURING METHOD FOR FIBER-REINFORCED PLASTIC MATERIAL | TORAY INDUSTRIES, INC. (JP) | 2017-12-21 | — | — | US | disclosed |
| EP-3230339-A1 | EPOXY RESIN COMPOSITION, PREPREG, FIBER-REINFORCED PLASTIC MATERIAL, AND MANUFACTURING METHOD FOR FIBER-REINFORCED PLASTIC MATERIAL | Toray Industries, Inc. (JP) | 2017-10-18 | — | — | EP | disclosed |
| CN-105435852-B | The preparation method of mesoporous composite material and catalyst and its preparation method and application and the dioxolanes of 2,2 dimethyl, 4 methyl 1,3 | 中国石油化工股份有限公司 | 2017-10-03 | — | — | CN | disclosed |
| CN-105435851-B | The preparation method of mesoporous composite material and catalyst and its preparation method and application and the dioxolanes of 2,2 dimethyl, 4 methyl 1,3 | 中国石油化工股份有限公司 | 2017-09-29 | — | — | CN | disclosed |
| CN-105214735-B | The preparation method of mesoporous composite material and catalyst and its preparation method and application and the dioxolanes of 2,2 dimethyl, 4 methyl 1,3 | 中国石油化工股份有限公司 | 2017-06-30 | — | — | CN | disclosed |
| CN-106902872-A | A kind of isocyanate polymeric catalyst and preparation method thereof, and its method for preparing PIC | 万华化学集团股份有限公司 | 2017-06-30 | — | — | CN | disclosed |
| WO-2016087935-A1 | EPOXY RESIN COMPOSITION, PREPREG, FIBER-REINFORCED PLASTIC MATERIAL, AND MANUFACTURING METHOD FOR FIBER-REINFORCED PLASTIC MATERIAL | TORAY INDUSTRIES, INC. (JP) | 2016-06-09 | — | — | WO | disclosed |
| US-20080227946-A1 | Thermosetting Composition and Curing Method Thereof | SHOWA DENKO K.K. | 2008-09-18 | — | — | US | disclosed |
| US-20070161685-A1 | HETEROCYCLIC CETP INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2007-07-12 | — | — | US | disclosed |
| US-20070135631-A1 | HETEROCYCLIC CETP INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2007-06-14 | — | — | US | disclosed |
| EP-1732980-A1 | THERMOSETTING COMPOSITION AND CURING METHOD THEREOF | SHOWA DENKO KABUSHIKI KAISHA (JP) | 2006-12-20 | — | — | EP | disclosed |
| US-20060257727-A1 | Reactive polymer-supporting porous film for battery seperator and use thereof | NITTO DENKO CORPORATION (JP) | 2006-11-16 | — | — | US | disclosed |
| EP-1667253-A1 | REACTIVE POLYMER-SUPPORTING POROUS FILM FOR BATTERY SEPARATOR AND USE THEREOF | NITTO DENKO CORPORATION (JP) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005097882-A1 | THERMOSETTING COMPOSITION AND CURING METHOD THEREOF | SHOWA DENKO K.K. (JP) | 2005-10-20 | — | — | WO | disclosed |
| US-6906116-B2 | Unsaturated polyester compounds, resins curable with actinic energy ray, processes for the production thereof, and curable compositions | KANAGAWA UNIVERSITY (JP) | 2005-06-14 | — | — | US | disclosed |
| US-20050064336-A1 | Unsaturated group-containing multi-branched compounds, curable compositions containing the same, and cured products thereof | TAIYO INK MANUFACTURING CO., LTD. (JP) | 2005-03-24 | — | — | US | disclosed |
| US-20040039087-A1 | Unsaturated polyester compounds, resins curable with actinic energy ray, processes for the production thereof, and curable compositions | KANAGAWA UNIVERSITY (JP) | 2004-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070161685-A1 | HETEROCYCLIC CETP INHIBITORS | CETP, CES1, NPC1 | ACE2 1301/4885KDM4E 1618/4885GRM1 4826/4885 |
| US-20230051807-A1 | PORPHYRIN PHOTOSENSITIZER AND COBALOXIME COCATALYST AND METHODS OF USE THEREOF | PPOX, HMBS, PNPO | ACE2 4418/4885KDM4E 2348/4885GRM1 2946/4885 |
| US-20070135631-A1 | HETEROCYCLIC CETP INHIBITORS | CETP, CES1, NPC1 | ACE2 1301/4885KDM4E 1618/4885GRM1 4826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.