Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 11/20 | 0.40 |
| ▸ | PGR | P06401 | 10/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6900478 | 0.51 | CYP2D6 (0.36) | MAPT | |
| SCHEMBL6901470 | 0.50 | CCR2 (0.36) | — | |
| SCHEMBL11687431 | 0.49 | — | — | |
| SCHEMBL13858888 | 0.48 | OPRM1 (0.58) | LMNA | |
| SCHEMBL20197052 | 0.48 | OPRM1 (0.39) | — | |
| SCHEMBL11616339 | 0.48 | CYP1A2 (0.35) | — | |
| SCHEMBL28157455 | 0.47 | ADH1B (0.38) | MAPT | |
| SCHEMBL11614377 | 0.47 | CYP1A2 (0.38) | — | |
| SCHEMBL11486416 | 0.47 | OPRM1 (0.55) | LMNA | |
| SCHEMBL325629 | 0.47 | OPRM1 (0.55) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238148-B1 | 15,16-METHYLENE-17-(1'-PROPENYL)-17,3'-OXIDOESTRA-4-EN-3-ONE DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING SAID DERIVATIVE | BAYER IP GMBH (DE) | 2012-10-24 | — | — | EP | disclosed |