Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 8/20 | 0.40 |
| ▸ | RARG | P13631 | 8/20 | 0.40 |
| ▸ | RARA | P10276 | 6/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.40 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL264275 | 0.77 | KMO (0.53) | KDM4EALDH1A1MAPK1HPGDHSD17B10 | |
| SCHEMBL6916181 | 0.75 | KDM4E (0.68) | KDM4EALDH1A1HPGDHSD17B10ENPP2 | |
| SCHEMBL29359975 | 0.75 | KDM4E (0.68) | KDM4EALDH1A1HPGDHSD17B10ENPP2 | |
| SCHEMBL18758 | 0.75 | KDM4E (0.68) | KDM4EALDH1A1HPGDHSD17B10ENPP2 | |
| SCHEMBL29594563 | 0.75 | KDM4E (0.68) | KDM4EALDH1A1HPGDHSD17B10ENPP2 | |
| SCHEMBL8185981 | 0.75 | TSHR (0.46) | ALDH1A1MAPK1HPGDTP53ALOX15 | |
| Hydrochloric Acid SCHEMBL1681545 | 0.73 | KDM4E (0.65) | KDM4EALDH1A1HPGDHSD17B10ENPP2 | |
| SCHEMBL1886411 | 0.73 | KDM4E (0.65) | KDM4EALDH1A1HPGDHSD17B10ENPP2 | |
| SCHEMBL20942846 | 0.73 | KDM4E (0.65) | KDM4EALDH1A1HPGDHSD17B10ENPP2 | |
| Bromide SCHEMBL8758652 | 0.73 | KDM4E (0.65) | KDM4EALDH1A1HPGDHSD17B10ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120277454-A1 | IHM-2 ORGANIC-INORGANIC HYBRID MATERIAL AND PROCESSES FOR PREPARATION | CNRS (FR) | 2012-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120277454-A1 | IHM-2 ORGANIC-INORGANIC HYBRID MATERIAL AND PROCESSES FOR PREPARATION | BMP2, BMPR2, HAO2 | KDM4E 2670/4885ALDH1A1 3530/4885MAPK1 4259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.