Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.34 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.34 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.34 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.33 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.33 |
| ▸ | PTGES | O14684 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13560544 | 0.90 | CCR2 (0.35) | CCR2NTSR1BRPF1GRM1 | |
| SCHEMBL13560471 | 0.86 | CLK1 (0.37) | CCR2DYRK1BPTGESL3MBTL1KDM4E | |
| SCHEMBL13560627 | 0.81 | CCR2 (0.39) | CCR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL13560466 | 0.78 | SRD5A2 (0.55) | — | |
| SCHEMBL13560510 | 0.77 | SRD5A2 (0.35) | PTGESL3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL13560477 | 0.77 | SRD5A2 (0.35) | L3MBTL1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL13560410 | 0.75 | SRD5A2 (0.34) | PTGESL3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL13560440 | 0.74 | CCR2 (0.39) | CCR2L3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL23176776 | 0.72 | NR1H2 (0.42) | CCR2CHEK1AURKADAPK3CSNK1A1 | |
| SCHEMBL29524657 | 0.72 | NR1H2 (0.42) | CCR2CHEK1AURKADAPK3CSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304419-B2 | Chemical compounds | GLAXOSMITHKLINE LLC (US) | 2012-11-06 | — | — | US | disclosed |