Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.31 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.31 |
| ▸ | PLA2G10 | O15496 | 4/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | PLA2G5 | P39877 | 3/20 | 0.30 |
| ▸ | B3GNT2 | Q9NY97 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13560567 | 0.90 | CCR2 (0.35) | CCR2BRPF1NTSR1GRM1 | |
| SCHEMBL13560440 | 0.81 | CCR2 (0.39) | CCR2 | |
| SCHEMBL13560471 | 0.79 | CLK1 (0.37) | CCR2GRM1 | |
| SCHEMBL13560533 | 0.79 | CCR2 (0.38) | CCR2BRPF1PLA2G10PLA2G2A | |
| SCHEMBL13560627 | 0.74 | CCR2 (0.39) | CCR2 | |
| SCHEMBL2003462 | 0.72 | BRPF1 (0.38) | CCR2BRPF1NTSR1 | |
| SCHEMBL13560510 | 0.71 | SRD5A2 (0.35) | — | |
| SCHEMBL3033212 | 0.70 | NR1H2 (0.41) | — | |
| SCHEMBL13560477 | 0.70 | SRD5A2 (0.35) | GRM1 | |
| SCHEMBL13560410 | 0.69 | SRD5A2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304419-B2 | Chemical compounds | GLAXOSMITHKLINE LLC (US) | 2012-11-06 | — | — | US | disclosed |