Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.30 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3033868 | 0.80 | NR1H2 (0.38) | MAPK14MAOATMEM97SIGMAR1SRD5A2 | |
| SCHEMBL13560585 | 0.79 | MAOA (0.36) | MAPK14MAOA | |
| SCHEMBL3023814 | 0.79 | MAOA (0.42) | MAPK14MAOA | |
| SCHEMBL13560510 | 0.78 | SRD5A2 (0.35) | MAOASRD5A2 | |
| SCHEMBL13560588 | 0.78 | MAPK14 (0.35) | MAPK14MAOATMEM97SIGMAR1SRD5A2 | |
| SCHEMBL13560410 | 0.77 | SRD5A2 (0.34) | MAOASRD5A2 | |
| SCHEMBL13560477 | 0.77 | SRD5A2 (0.35) | MAOASRD5A2 | |
| SCHEMBL13560466 | 0.75 | SRD5A2 (0.55) | SRD5A2 | |
| SCHEMBL13560471 | 0.71 | CLK1 (0.37) | — | |
| SCHEMBL13560567 | 0.70 | CCR2 (0.35) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304419-B2 | Chemical compounds | GLAXOSMITHKLINE LLC (US) | 2012-11-06 | — | — | US | disclosed |