Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.57 |
| ▸ | FABP4 | P15090 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
| ▸ | EDNRB | P24530 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13563240 | 0.83 | HTR6 (0.53) | HTR6FABP4CA1CA2HSD17B10 | |
| SCHEMBL13563338 | 0.82 | HTR6 (0.53) | HTR6FABP4CA1CA2HSD17B10 | |
| SCHEMBL14624291 | 0.82 | HTR6 (0.59) | HTR6FABP4CA1CA2HSD17B10 | |
| SCHEMBL13478781 | 0.77 | MTNR1A (0.51) | HTR6FABP4KMT2AMAPT | |
| SCHEMBL13563336 | 0.76 | HTR6 (0.46) | HTR6FABP4CA1CA2PTGS1 | |
| SCHEMBL14217957 | 0.74 | HTR6 (0.52) | HTR6CA1CA2 | |
| SCHEMBL15899412 | 0.73 | HTR6 (0.57) | HTR6CA1CA2HSD17B10MEN1 | |
| SCHEMBL13626290 | 0.72 | HTR6 (0.54) | HTR6CA1CA2HSD17B10PTGS1 | |
| SCHEMBL14218039 | 0.72 | HTR6 (0.43) | HTR6FABP4CA1CA2HSD17B10 | |
| SCHEMBL13478801 | 0.72 | HTR6 (0.55) | HTR6FABP4CA1CA2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2297100-B1 | TETRAHYDROCYCLOPENTA[B]INDOLE ANDROGEN RECEPTOR MODULATORS | LILLY CO ELI (US) | 2012-10-31 | — | — | EP | disclosed |