Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SCARB1 | Q8WTV0 | 6/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13563337 | 0.85 | SCARB1 (0.49) | HTR6PTGS1PTGS2CA1CA2 | |
| SCHEMBL13563240 | 0.82 | HTR6 (0.53) | HTR6PTGS1PTGS2CA1CA2 | |
| SCHEMBL13563257 | 0.76 | HTR6 (0.46) | HTR6PTGS1PTGS2CA1CA2 | |
| SCHEMBL13563320 | 0.73 | HTR6 (0.44) | HTR6PTGS1PTGS2CA1CA2 | |
| SCHEMBL13563274 | 0.72 | HTR6 (0.57) | HTR6PTGS1PTGS2CA1CA2 | |
| SCHEMBL14217957 | 0.72 | HTR6 (0.52) | HTR6CA1CA2 | |
| SCHEMBL13478801 | 0.70 | HTR6 (0.55) | HTR6PTGS1PTGS2CA1CA2 | |
| SCHEMBL15899412 | 0.69 | HTR6 (0.57) | HTR6PTGS1PTGS2CA1CA2 | |
| SCHEMBL15899271 | 0.68 | HTR6 (0.54) | HTR6PTGS1PTGS2CA1CA2 | |
| SCHEMBL13626053 | 0.68 | HTR6 (0.46) | HTR6PTGS1PTGS2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140448-A1 | TETRAHYDROCYCLOPENTA[B]INDOLE ANDROGEN RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2009-11-19 | — | — | WO | disclosed |