Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17090293 | 0.86 | KIF11 (0.48) | PPARAADRA2AHIF1AKIF11FFAR1 | |
| SCHEMBL13565078 | 0.84 | MAPT (0.45) | PPARAHIF1ACA1CA2CA12 | |
| SCHEMBL13565602 | 0.84 | SLC22A12 (0.44) | PPARAKIF11 | |
| SCHEMBL13566041 | 0.84 | CA1 (0.39) | PPARAADRA2ACA1CA2KIF11 | |
| SCHEMBL11936106 | 0.83 | PPARA (0.43) | PPARAHIF1ACA1CA2CA12 | |
| SCHEMBL13565693 | 0.82 | MAPT (0.42) | PPARAHIF1ACA1CA2CA12 | |
| SCHEMBL13565993 | 0.82 | PPARA (0.55) | PPARAADRA2ACA1CA2KIF11 | |
| SCHEMBL13565065 | 0.80 | KDM4E (0.44) | HIF1ACA1CA2CA12CA9 | |
| SCHEMBL13565690 | 0.79 | PPARA (0.46) | PPARAFFAR1 | |
| SCHEMBL11936067 | 0.79 | CA1 (0.45) | HIF1ACA1CA2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |
| US-8299265-B2 | Amine derivatives having NPY Y5 receptor antagonistic activity and the uses thereof | SHIONOGI & CO., LTD. (JP) | 2012-10-30 | — | — | US | disclosed |