Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | DRD3 | P35462 | 4/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESRRA | P11474 | 1/20 | 0.37 |
| ▸ | ESRRG | P62508 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565564 | 1.00 | DRD2 (0.43) | DRD2DRD3ADRB1RORCGAA | |
| SCHEMBL11935094 | 0.91 | HDAC3 (0.46) | GAANPY5RUSP30 | |
| SCHEMBL17090135 | 0.91 | HDAC3 (0.46) | GAANPY5RUSP30 | |
| SCHEMBL13565425 | 0.91 | ALDH1A1 (0.41) | GAAMAPTALOX15ALOX12MAPK1 | |
| SCHEMBL11935083 | 0.90 | ALDH1A1 (0.42) | GAAMAPTALOX15MAPK1GFER | |
| SCHEMBL11935435 | 0.90 | NPY5R (0.38) | ADRB1NPY5R | |
| SCHEMBL13439167 | 0.90 | NPY5R (0.38) | ADRB1NPY5R | |
| SCHEMBL11935093 | 0.89 | MAPT (0.45) | GAAMAPTALOX15ALOX12MAPK1 | |
| SCHEMBL13565507 | 0.89 | GPR119 (0.46) | DRD2DRD3MAPT | |
| SCHEMBL17090125 | 0.89 | GPR119 (0.46) | DRD2DRD3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |