Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 4/20 | 0.42 |
| ▸ | CNR1 | P21554 | 3/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ALPL | P05186 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17090476 | 1.00 | MET (0.45) | METMCHR1HPGDSCNR2CNR1 | |
| SCHEMBL13565703 | 0.86 | NR3C1 (0.42) | METMCHR1CNR2ALDH1A1LMNA | |
| SCHEMBL11936220 | 0.86 | NR3C1 (0.42) | METMCHR1CNR2ALDH1A1LMNA | |
| SCHEMBL13565676 | 0.85 | MET (0.45) | METMCHR1HPGDSALDH1A1ALPL | |
| SCHEMBL13565722 | 0.82 | MET (0.43) | METMCHR1HPGDSCNR2CNR1 | |
| SCHEMBL11935223 | 0.80 | CRHR1 (0.44) | MCHR1CNR2CNR1ALDH1A1KMT2A | |
| SCHEMBL13438902 | 0.80 | CRHR1 (0.44) | MCHR1CNR2CNR1ALDH1A1KMT2A | |
| SCHEMBL10113220 | 0.80 | EPHX2 (0.58) | HPGDSCNR2CNR1KDM4ELMNA | |
| SCHEMBL13203770 | 0.80 | EPHX2 (0.58) | HPGDSCNR2CNR1KDM4ELMNA | |
| SCHEMBL13565617 | 0.79 | MET (0.40) | METMCHR1CNR2KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8299265-B2 | Amine derivatives having NPY Y5 receptor antagonistic activity and the uses thereof | SHIONOGI & CO., LTD. (JP) | 2012-10-30 | — | — | US | disclosed |