Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 5/20 | 0.39 |
| ▸ | CNR1 | P21554 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CISD1 | Q9NZ45 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13564906 | 0.86 | LMNA (0.39) | L3MBTL1ALDH1A1GAAMAPTLMNA | |
| SCHEMBL10113565 | 0.85 | CNR2 (0.45) | ALDH1A1CNR2CNR1 | |
| SCHEMBL13564897 | 0.84 | LMNA (0.38) | L3MBTL1NPC1RAB9ALMNAHTT | |
| SCHEMBL13565781 | 0.84 | GRIA1 (0.43) | L3MBTL1MEN1NPC1ALDH1A1GAA | |
| SCHEMBL17090510 | 0.83 | MAPT (0.52) | MEN1NPC1GAAMAPTRAB9A | |
| SCHEMBL11934985 | 0.81 | NPC1 (0.48) | NPC1ALDH1A1RAB9ALMNAHTT | |
| SCHEMBL13565817 | 0.81 | THRB (0.46) | ALDH1A1MAPTKMT2ALMNAHTT | |
| SCHEMBL11934986 | 0.79 | NR5A1 (0.45) | L3MBTL1MEN1NPC1ALDH1A1GAA | |
| SCHEMBL13565681 | 0.79 | PNLIP (0.42) | LMNAHTTCNR2 | |
| SCHEMBL10113573 | 0.75 | HDAC3 (0.48) | ALDH1A1CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |
| US-8299265-B2 | Amine derivatives having NPY Y5 receptor antagonistic activity and the uses thereof | SHIONOGI & CO., LTD. (JP) | 2012-10-30 | — | — | US | disclosed |