Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11934985 | 0.84 | NPC1 (0.48) | EPHX1CNR2NPC1RAB9ALMNA | |
| SCHEMBL13565497 | 0.84 | GRIA1 (0.44) | MEN1KMT2APOLBDGAT1PABPC1 | |
| SCHEMBL10113564 | 0.84 | SMN1; SMN2 (0.48) | MEN1KMT2APOLBDGAT1LMNA | |
| SCHEMBL13565666 | 0.82 | ADAMTS4 (0.42) | MEN1KMT2AIDO1RAB9ALMNA | |
| SCHEMBL13565681 | 0.80 | PNLIP (0.42) | POLBEPHX1CNR2LMNAHTT | |
| SCHEMBL13565817 | 0.79 | THRB (0.46) | KMT2AEPHX1CNR2CYP2D6LMNA | |
| SCHEMBL11934993 | 0.79 | MEN1 (0.42) | MEN1KMT2APOLBDGAT1PABPC1 | |
| SCHEMBL13565283 | 0.76 | ALDH1A1 (0.50) | MEN1KMT2AEPHX1CNR2CYP3A4 | |
| SCHEMBL11934794 | 0.75 | HPGD (0.46) | MEN1KMT2APOLBEPHX1CNR2 | |
| SCHEMBL13438596 | 0.75 | HPGD (0.46) | MEN1KMT2APOLBEPHX1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |
| US-8299265-B2 | Amine derivatives having NPY Y5 receptor antagonistic activity and the uses thereof | SHIONOGI & CO., LTD. (JP) | 2012-10-30 | — | — | US | disclosed |