Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BUB1 | O43683 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13567987 | 1.00 | L3MBTL1 (0.43) | L3MBTL1OPRM1OPRL1JAK2JAK1 | |
| SCHEMBL24438513 | 0.85 | L3MBTL1 (0.44) | L3MBTL1OPRM1OPRL1JAK2JAK1 | |
| SCHEMBL29751192 | 0.84 | L3MBTL1 (0.42) | L3MBTL1JAK2JAK1SIGMAR1ABCB1 | |
| SCHEMBL3828306 | 0.84 | OPRM1 (0.47) | OPRM1OPRL1TRPM8SIGMAR1FFAR1 | |
| SCHEMBL3834261 | 0.84 | OPRM1 (0.47) | OPRM1OPRL1TRPM8SIGMAR1FFAR1 | |
| SCHEMBL3828309 | 0.84 | OPRM1 (0.47) | OPRM1OPRL1TRPM8SIGMAR1FFAR1 | |
| SCHEMBL23857882 | 0.82 | MGLL (0.49) | L3MBTL1JAK2JAK1HSD11B1HDAC3 | |
| SCHEMBL27091161 | 0.81 | L3MBTL1 (0.42) | L3MBTL1OPRM1OPRL1HSD11B1HDAC3 | |
| SCHEMBL29308988 | 0.80 | AGTR2 (0.47) | L3MBTL1JAK2JAK1HSD11B1SIGMAR1 | |
| SCHEMBL21070888 | 0.80 | SMN1; SMN2 (0.42) | OPRM1JAK2JAK1HSD11B1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090312310-A1 | Imidazothiazole derivatives | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-12-17 | — | — | US | disclosed |
| US-20090312310-A1 | Imidazothiazole derivatives | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312310-A1 | Imidazothiazole derivatives | TP53, MDM2, TP53BP1 | L3MBTL1 299/4885OPRM1 4283/4885OPRL1 4394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.