Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | DRD4 | P21917 | 6/20 | 0.64 |
| ▸ | DRD3 | P35462 | 5/20 | 0.64 |
| ▸ | DRD2 | P14416 | 4/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | CASP7 | P55210 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29378232 | 0.89 | KDM4E (0.65) | ALDH1A1KDM4ETDP1POLBTSHR | |
| SCHEMBL22533031 | 0.89 | KDM4E (0.65) | ALDH1A1KDM4ETDP1POLBTSHR | |
| SCHEMBL25672951 | 0.87 | KDM4E (0.63) | ALDH1A1KDM4ETDP1POLBTSHR | |
| SCHEMBL15937598 | 0.87 | DRD4 (0.67) | ALDH1A1KDM4ETDP1POLBTSHR | |
| SCHEMBL8744970 | 0.85 | CACNA1G (0.57) | ALDH1A1KDM4ETDP1POLBTSHR | |
| Hydrochloric Acid SCHEMBL8745014 | 0.84 | CACNA1G (0.56) | ALDH1A1KDM4ETDP1POLBTSHR | |
| SCHEMBL8550773 | 0.82 | DRD4 (0.55) | ALDH1A1KDM4ETDP1POLBTSHR | |
| SCHEMBL1537856 | 0.82 | KDM4E (0.55) | ALDH1A1KDM4ETDP1POLBTSHR | |
| SCHEMBL6864941 | 0.82 | DRD4 (0.81) | ALDH1A1KDM4EDRD4DRD3DRD2 | |
| SCHEMBL19212045 | 0.82 | TRPC5 (0.52) | ALDH1A1KDM4ETDP1POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009156724-A2 | NOVEL COMPOUNDS | ISIS INNOVATION LIMITED (GB) | 2009-12-30 | — | — | WO | disclosed |