Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | DRD4 | P21917 | 2/20 | 0.54 |
| ▸ | DRD3 | P35462 | 2/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8745014 | 0.99 | CACNA1G (0.56) | CACNA1GALDH1A1KDM4EPOLBTSHR | |
| SCHEMBL13568797 | 0.85 | ALDH1A1 (0.71) | ALDH1A1KDM4EPOLBTSHRHSD17B10 | |
| SCHEMBL8745020 | 0.84 | ITGB3 (0.52) | ALDH1A1TDP1DRD4DRD3DRD2 | |
| SCHEMBL8744984 | 0.84 | ATM (0.70) | ALDH1A1KDM4EDRD4DRD2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8745009 | 0.83 | ATM (0.68) | ALDH1A1KDM4EDRD4DRD2SMN1; SMN2 | |
| SCHEMBL8691440 | 0.81 | DRD4 (0.70) | CACNA1GALDH1A1DRD4DRD3DRD2 | |
| SCHEMBL22533031 | 0.81 | KDM4E (0.65) | CACNA1GALDH1A1KDM4EPOLBTSHR | |
| SCHEMBL29378232 | 0.81 | KDM4E (0.65) | CACNA1GALDH1A1KDM4EPOLBTSHR | |
| SCHEMBL8744973 | 0.81 | MAPK1 (0.70) | ALDH1A1KDM4EPOLBTSHRDRD4 | |
| Hydrochloric Acid SCHEMBL8690310 | 0.80 | DRD4 (0.68) | CACNA1GDRD4DRD3DRD2ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0753515-A2 | Benzylpiperazine derivatives as antiallergic and anti-inflammatory agents | Senju Pharmaceutical Co., Ltd. (JP) | 1997-01-15 | — | — | EP | claimed |
| EP-0753515-A2 | Benzylpiperazine derivatives as antiallergic and anti-inflammatory agents | Senju Pharmaceutical Co., Ltd. (JP) | 1997-01-15 | — | — | EP | disclosed |