Glycerin

Glycerin

SCHEMBL1357013

O=C(O)OC(=O)O.OCC(O)CO.OCC(O)CO

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.53
ALDH1A1 P00352 1/20 0.53
OR51E2 Q9H255 1/20 0.41
SLC22A6 Q4U2R8 1/20 0.36
THRB P10828 1/20 0.36
PDE4A P27815 1/20 0.33
KDM4E B2RXH2 1/20 0.32
DUSP3 P51452 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
USP2 O75604 1/20 0.31
SLCO1B1 Q9Y6L6 1/20 0.31
GABRR1 P24046 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycerin SCHEMBL7159292 1.00 LMNA (0.53) LMNAALDH1A1OR51E2SLC22A6THRB
Glycerin SCHEMBL30900516 0.89 LMNA (0.47) LMNAALDH1A1OR51E2SLC22A6THRB
Glycerin SCHEMBL28900065 0.89 LMNA (0.47) LMNAALDH1A1OR51E2SLC22A6THRB
Glycerin SCHEMBL3708808 0.85 LMNA (0.43) LMNAALDH1A1OR51E2SLC22A6THRB
Glycerin SCHEMBL10780445 0.83 LMNA (0.41) LMNAALDH1A1OR51E2KDM4EDUSP3
Glycerin SCHEMBL30929982 0.81 LMNA (0.69) LMNAALDH1A1OR51E2SLC22A6THRB
Glycerin SCHEMBL7030045 0.81 LMNA (0.69) LMNAALDH1A1OR51E2SLC22A6THRB
Glycerin SCHEMBL44491 0.81 LMNA (0.69) LMNAALDH1A1OR51E2SLC22A6THRB
Glycerin SCHEMBL28563108 0.81 LMNA (0.69) LMNAALDH1A1OR51E2SLC22A6THRB
Glycerin SCHEMBL4671978 0.81 LMNA (0.69) LMNAALDH1A1OR51E2SLC22A6THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210032495-A1 WATERBORNE ISOCYANATE-FREE POLYURETHANE EPOXY HYBRID COATINGS THE UNIVERSITY OF AKRON 2021-02-04 US claimed
US-20110288230-A1 METHOD FOR PREPARING POLYHYDROXY-URETHANES RHODIA OPERATIONS (FR) 2011-11-24 US claimed
US-20090312502-A1 Method for preparing polyhydroxy-urethanes RHODIA OPERATIONS (FR) 2009-12-17 US claimed
EP-0272664-B1 CURABLE MIXTURES AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1992-05-27 EP claimed
EP-3375812-B1 THIO EPOXY RESINS AND METHOD FOR PREPARATION PERFORMANCE CHEMICALS HANDELS GMBH (DE) 2024-04-24 EP disclosed
US-11932774-B2 Waterborne isocyanate-free polyurethane epoxy hybrid coatings THE UNIVERSITY OF AKRON (US) 2024-03-19 US disclosed
CN-116438120-A Aromatic diol compound, diepoxide compound, polymer prepared from such compound, and process for producing the same SWIMC有限公司 2023-07-14 CN disclosed
WO-2022238341-A1 MELT-MODIFIED THERMOPLASTIC POLYURETHANES AND COMPOSITION COMPRISING THE SAME Sorbonne Université (FR) 2022-11-17 WO disclosed
EP-4089134-A1 THERMOPLASTIC POLYURETHANES MODIFIED BY MELTING AND COMPOSITION CONTAINING THEM Sorbonne Université (FR) 2022-11-16 EP disclosed
US-20210032495-A1 WATERBORNE ISOCYANATE-FREE POLYURETHANE EPOXY HYBRID COATINGS THE UNIVERSITY OF AKRON 2021-02-04 US disclosed
CN-107698748-B Dynamic polymer of hybrid cross-linked network and application thereof 翁秋梅 2020-03-10 CN disclosed
CN-106714856-B Composition containing glycosaminoglycan and protein 尚卓耐斯特公司 2020-03-03 CN disclosed
EP-3193952-A1 COMPOSITION CONTAINING GLYCOSAMINOGLYCANS AND PROTEINS Chondronest SA (CH) 2017-07-26 EP disclosed
WO-2016042434-A1 COMPOSITION CONTAINING GLYCOSAMINOGLYCANS AND PROTEINS SWISSBIOTECH SA (CH) 2016-03-24 WO disclosed
US-9242956-B2 Method for producing polyglycerol (poly)carbonate RHODIA OPERATIONS (FR) 2016-01-26 US disclosed
US-20150152079-A1 Method for producing polyglycerol (poly)carbonate CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2015-06-04 US disclosed
US-20110288230-A1 METHOD FOR PREPARING POLYHYDROXY-URETHANES RHODIA OPERATIONS (FR) 2011-11-24 US disclosed
US-8017719-B2 Method for preparing polyhydroxy-urethanes RHODIA OPERATIONS (FR) 2011-09-13 US disclosed
US-20090312502-A1 Method for preparing polyhydroxy-urethanes RHODIA OPERATIONS (FR) 2009-12-17 US disclosed
US-6008314-A HARDENERS OBTAINED FROM REACTION OF: AMINOURETHANES OBTAINED BY REACTING CYCLIC CARBONATES WITH PRIMARY AMINES; WATER THINNABLE EPOXIDES OBTAINED BY REACTING POLYOXYALKYLENE AMINES WITH EPOXIDES; AND AMINES; FORMING MULTILAYER COATINGS HERBERTS GMBH (DE) 1999-12-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150152079-A1 Method for producing polyglycerol (poly)carbonate PHOSPHO1, ALG1, AGL LMNA 974/4885ALDH1A1 4234/4885OR51E2 4499/4885
US-20110288230-A1 METHOD FOR PREPARING POLYHYDROXY-URETHANES UROD, HPD, ALKBH3 LMNA 2578/4885ALDH1A1 2408/4885OR51E2 1501/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.