Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycerin SCHEMBL7038290 | 0.87 | ALDH1A1 (0.56) | LMNAALDH1A1TSHRHSD17B10TDP1 | |
| Glycerin SCHEMBL7159292 | 0.85 | LMNA (0.53) | LMNAALDH1A1OR51E2KDM4EDUSP3 | |
| Glycerin SCHEMBL1357013 | 0.85 | LMNA (0.53) | LMNAALDH1A1OR51E2KDM4EDUSP3 | |
| Glycerin SCHEMBL28900065 | 0.80 | LMNA (0.47) | LMNAALDH1A1OR51E2KDM4EDUSP3 | |
| Glycerin SCHEMBL30900516 | 0.80 | LMNA (0.47) | LMNAALDH1A1OR51E2KDM4EDUSP3 | |
| Glycerin SCHEMBL27786407 | 0.79 | ALDH1A1 (0.41) | LMNAALDH1A1TSHRHSD17B10TDP1 | |
| Glycerin SCHEMBL10780445 | 0.79 | LMNA (0.41) | LMNAALDH1A1OR51E2KDM4EDUSP3 | |
| Glycerin SCHEMBL6374082 | 0.79 | ALDH1A1 (0.41) | LMNAALDH1A1TSHRHSD17B10TDP1 | |
| Glycerin SCHEMBL1685689 | 0.79 | LMNA (0.60) | LMNAALDH1A1TDP1OR51E2KDM4E | |
| Glycerin SCHEMBL1685695 | 0.79 | LMNA (0.60) | LMNAALDH1A1TDP1OR51E2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2491918-B1 | Polyglyceryl compounds and compositions | JOHNSON & JOHNSON CONSUMER (US) | 2015-05-06 | — | — | EP | disclosed |
| EP-2491916-B1 | Polyglyceryl compounds and compositions | JOHNSON & JOHNSON CONSUMER (US) | 2015-03-11 | — | — | EP | disclosed |
| EP-2491917-B1 | Polyglyceryl compounds and compositions | JOHNSON & JOHNSON CONSUMER (US) | 2014-12-17 | — | — | EP | disclosed |
| US-8778864-B2 | Polyglyceryl compounds and compositions | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2014-07-15 | — | — | US | disclosed |
| US-8455418-B2 | Polyglyceryl compounds comprising a methyl glucoside or sorbitan remnant and compositions containing same | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2013-06-04 | — | — | US | disclosed |
| US-8394755-B2 | Polyglyceryl compounds and compositions | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2013-03-12 | — | — | US | disclosed |
| EP-2491917-A1 | Polyglyceryl compounds and compositions | Johnson & Johnson Consumer Companies Inc. (US) | 2012-08-29 | — | — | EP | disclosed |
| EP-2491918-A1 | Polyglyceryl compounds and compositions | Johnson & Johnson Consumer Companies Inc. (US) | 2012-08-29 | — | — | EP | disclosed |
| EP-2491916-A1 | Polyglyceryl compounds and compositions | Johnson & Johnson Consumer Companies Inc. (US) | 2012-08-29 | — | — | EP | disclosed |
| US-8211850-B2 | Polyglyceryl compounds and compositions | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2012-07-03 | — | — | US | disclosed |
| US-20120122758-A1 | POLYGLYCERYL COMPOUNDS AND COMPOSITIONS | KENVUE BRANDS LLC | 2012-05-17 | — | — | US | disclosed |
| US-20120122755-A1 | POLYGLYCERYL COMPOUNDS AND COMPOSITIONS | JOHNSON & JOHNSON CONSUMER INC. | 2012-05-17 | — | — | US | disclosed |
| US-20120123103-A1 | POLYGLYCERYL COMPOUNDS AND COMPOSITIONS | KENVUE BRANDS LLC | 2012-05-17 | — | — | US | disclosed |
| US-20120123104-A1 | POLYGLYCERYL COMPOUNDS AND COMPOSITIONS | KENVUE BRANDS LLC | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120123104-A1 | POLYGLYCERYL COMPOUNDS AND COMPOSITIONS | PHOSPHO1, SGMS1, SGMS2 | LMNA 705/4885ALDH1A1 4219/4885TSHR 4727/4885 |
| US-20120122755-A1 | POLYGLYCERYL COMPOUNDS AND COMPOSITIONS | PHOSPHO1, SGMS1, SGMS2 | LMNA 705/4885ALDH1A1 4219/4885TSHR 4727/4885 |
| US-20120122758-A1 | POLYGLYCERYL COMPOUNDS AND COMPOSITIONS | PHOSPHO1, SGMS1, SGMS2 | LMNA 705/4885ALDH1A1 4219/4885TSHR 4727/4885 |
| US-20120123103-A1 | POLYGLYCERYL COMPOUNDS AND COMPOSITIONS | PHOSPHO1, SGMS1, SGMS2 | LMNA 705/4885ALDH1A1 4219/4885TSHR 4727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.