Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | C1S | P09871 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12919933 | 0.74 | AKT1 (0.41) | ALDH1A1KMT2APKMATMMAPT | |
| SCHEMBL24648534 | 0.70 | MAOB (0.41) | ALDH1A1MAPTL3MBTL1LMNAMAPK1 | |
| SCHEMBL25490750 | 0.68 | ALDH1A1 (0.38) | ALDH1A1KMT2AKDM4EPKMATM | |
| SCHEMBL23837641 | 0.68 | NFE2L2 (0.54) | ALDH1A1KMT2AKDM4EMAPTTSHR | |
| SCHEMBL24254437 | 0.66 | MEN1 (0.42) | ALDH1A1KMT2AATMMAPTLMNA | |
| SCHEMBL6258204 | 0.66 | MEN1 (0.42) | ALDH1A1KMT2AATMMAPTLMNA | |
| SCHEMBL22663851 | 0.66 | ALDH1A1 (0.43) | ALDH1A1KMT2AKDM4EPKMATM | |
| SCHEMBL330617 | 0.65 | ALDH1A1 (0.42) | ALDH1A1KMT2AMAPTLMNACYP1A2 | |
| SCHEMBL23319601 | 0.65 | KMT2A (0.33) | ALDH1A1KMT2AMAPTL3MBTL1PRSS1 | |
| SCHEMBL10479698 | 0.65 | DEGS1 (0.43) | KMT2AATMMAPTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2133347-A1 | 1-BIARYLAZETIDINONE DERIVATIVES | Teijin Pharma Limited (JP) | 2009-12-16 | — | — | EP | disclosed |