Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 16/20 | 0.55 |
| ▸ | MMP2 | P08253 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 12/20 | 0.52 |
| ▸ | MMP1 | P03956 | 11/20 | 0.52 |
| ▸ | ADAM17 | P78536 | 10/20 | 0.52 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26770427 | 0.76 | ALDH1A1 (0.73) | MMP9MMP2ALDH1A1MMP13MMP1 | |
| SCHEMBL13570527 | 0.76 | ALDH1A1 (0.63) | MMP9MMP2ALDH1A1MMP13MMP1 | |
| SCHEMBL8843296 | 0.75 | TAS2R14 (0.58) | KEAP1NFE2L2 | |
| SCHEMBL13570529 | 0.75 | MMP9 (0.80) | MMP9MMP2ALDH1A1MMP13MMP1 | |
| SCHEMBL13570600 | 0.75 | MMP9 (0.80) | MMP9MMP2ALDH1A1MMP13MMP1 | |
| SCHEMBL13570580 | 0.75 | MMP9 (0.80) | MMP9MMP2ALDH1A1MMP13MMP1 | |
| SCHEMBL13640701 | 0.74 | MMP9 (0.69) | MMP9MMP2ALDH1A1MMP13MMP1 | |
| SCHEMBL13639279 | 0.74 | MMP9 (0.69) | MMP9MMP2ALDH1A1MMP13MMP1 | |
| SCHEMBL16330734 | 0.74 | MMP9 (0.61) | MMP9MMP2ALDH1A1MMP13MMP1 | |
| SCHEMBL16330733 | 0.74 | MMP9 (0.61) | MMP9MMP2ALDH1A1MMP13MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2520573-A1 | Compounds with matrix-metalloproteinase inhibitory activity | Westfälische Wilhelms-Universität Münster (DE) | 2012-11-07 | — | — | EP | disclosed |