Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 7/20 | 0.65 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.65 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.65 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.65 |
| ▸ | DRD2 | P14416 | 3/20 | 0.65 |
| ▸ | DRD3 | P35462 | 3/20 | 0.65 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.65 |
| ▸ | HTR1A | P08908 | 2/20 | 0.65 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.65 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.65 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.65 |
| ▸ | HTR2A | P28223 | 2/20 | 0.65 |
| ▸ | HTR2B | P41595 | 2/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.65 |
| ▸ | HTR7 | P34969 | 1/20 | 0.65 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14301033 | 0.81 | ADRA1A (0.70) | ADRA1AADRA1DADRA1BADRB2DRD2 | |
| Tamsulosin SCHEMBL30361066 | 0.79 | ADRA1A (1.00) | ADRA1AADRA1DADRA1BADRB2DRD2 | |
| Tamsulosin SCHEMBL29363851 | 0.79 | ADRA1A (1.00) | ADRA1AADRA1DADRA1BADRB2DRD2 | |
| Tamsulosin SCHEMBL29599595 | 0.79 | ADRA1A (1.00) | ADRA1AADRA1DADRA1BADRB2DRD2 | |
| Tamsulosin SCHEMBL34378 | 0.79 | ADRA1A (1.00) | ADRA1AADRA1DADRA1BADRB2DRD2 | |
| Tamsulosin SCHEMBL29566149 | 0.79 | ADRA1A (1.00) | ADRA1AADRA1DADRA1BADRB2DRD2 | |
| Tamsulosin SCHEMBL29588704 | 0.79 | ADRA1A (1.00) | ADRA1AADRA1DADRA1BADRB2DRD2 | |
| Tamsulosin SCHEMBL53998 | 0.79 | ADRA1A (1.00) | ADRA1AADRA1DADRA1BADRB2DRD2 | |
| SCHEMBL19068575 | 0.79 | ADRA1A (0.81) | ADRA1AADRA1DADRA1BADRB2DRD2 | |
| Tamsulosin SCHEMBL30465862 | 0.79 | ADRA1A (1.00) | ADRA1AADRA1DADRA1BADRB2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394813-B2 | Active agent delivery systems and methods for protecting and administering active agents | SHIRE LLC (US) | 2013-03-12 | — | — | US | disclosed |
| US-20090306228-A1 | ACTIVE AGENT DELIVERY SYSTEMS AND METHODS FOR PROTECTING AND ADMINISTERING ACTIVE AGENTS | SHIRE LLC (US) | 2009-12-10 | — | — | US | disclosed |
| US-20090253792-A1 | ACTIVE AGENT DELIVERY SYSTEMS AND METHODS FOR PROTECTING AND ADMINISTERING ACTIVE AGENTS | SHIRE LLC (US) | 2009-10-08 | — | — | US | disclosed |
| US-7427600-B2 | Active agent delivery systems and methods for protecting and administering active agents | SHIRE LLC (US) | 2008-09-23 | — | — | US | disclosed |
| US-20070232529-A1 | mesalamine covalently attached to carrier peptide at C-terminus, interspersed and/or side chain; releasing into bloodstream; reducing dosage | NEW RIVER PHARMACEUTICALS INC. (US) | 2007-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253792-A1 | ACTIVE AGENT DELIVERY SYSTEMS AND METHODS FOR PROTECTING AND ADMINISTERING ACTIVE AGENTS | HDGF, CTSA, IAPP | ADRA1A 1742/4885ADRA1D 3128/4885ADRA1B 2618/4885 |
| US-20090306228-A1 | ACTIVE AGENT DELIVERY SYSTEMS AND METHODS FOR PROTECTING AND ADMINISTERING ACTIVE AGENTS | HDGF, CTSA, IAPP | ADRA1A 1742/4885ADRA1D 3128/4885ADRA1B 2618/4885 |
| US-20070232529-A1 | mesalamine covalently attached to carrier peptide at C-terminus, interspersed and/or side chain; releasing into bloodstream; reducing dosage | VIP, BST2, FCGR3B | ADRA1A 1299/4885ADRA1D 2164/4885ADRA1B 1875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.