20-Hydroxyecdysone

20-Hydroxyecdysone

SCHEMBL13576228

CC(C)(O)CC[C@@H](O)[C@](C)(O)C1CC[C@@]2(O)C3=CC(=O)C4C[C@@H](O)[C@@H](O)CC4(C)C3CCC12C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.71
▸ KMT2A Q03164 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
20-Hydroxyecdysone SCHEMBL20033388 1.00 MEN1 (0.71) MEN1KMT2A
20-Hydroxyecdysone SCHEMBL9481370 1.00 MEN1 (0.71) MEN1KMT2A
20-Hydroxyecdysone SCHEMBL8193574 1.00 MEN1 (0.71) MEN1KMT2A
20-Hydroxyecdysone SCHEMBL6243068 1.00 MEN1 (0.71) MEN1KMT2A
20-Hydroxyecdysone SCHEMBL8193572 1.00 MEN1 (0.71) MEN1KMT2A
20-Hydroxyecdysone SCHEMBL990951 1.00 MEN1 (0.71) MEN1KMT2A
20-Hydroxyecdysone SCHEMBL22087 1.00 MEN1 (0.71) MEN1KMT2A
20-Hydroxyecdysone SCHEMBL8861138 1.00 MEN1 (0.71) MEN1KMT2A
20-Hydroxyecdysone SCHEMBL17580332 1.00 MEN1 (0.71) MEN1KMT2A
20-Hydroxyecdysone SCHEMBL8861142 1.00 MEN1 (0.71) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9243263-B2 Steroidal ligands and their use in gene switch modulation INTREXON CORPORATION (US) 2016-01-26 — — US disclosed
US-9243263-B2 Steroidal ligands and their use in gene switch modulation INTREXON CORPORATION (US) 2016-01-26 — — US disclosed
US-20140057349-A1 Steroidal Ligands and Their Use in Gene Switch Modulation INTREXON CORPORATION (US) 2014-02-27 — — US disclosed
US-20140057349-A1 Steroidal Ligands and Their Use in Gene Switch Modulation INTREXON CORPORATION (US) 2014-02-27 — — US disclosed
US-8536354-B2 Steroidal ligands and their use in gene switch modulation INTREXON CORPORATION (US) 2013-09-17 — — US disclosed
US-8536354-B2 Steroidal ligands and their use in gene switch modulation INTREXON CORPORATION (US) 2013-09-17 — — US disclosed
US-20090298175-A1 Steroidal Ligands and Their Use in Gene Switch Modulation INTREXON CORPORATION 2009-12-03 — — US disclosed
US-20090298175-A1 Steroidal Ligands and Their Use in Gene Switch Modulation INTREXON CORPORATION 2009-12-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090298175-A1 Steroidal Ligands and Their Use in Gene Switch Modulation ESRRB, NR3C1, ESRRA MEN1 4342/4885KMT2A 2717/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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