SCHEMBL1357643

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6840228	0.90	ROCK2 (0.53)	ROCK2PIM1PIM3FFAR4MGLL
	SCHEMBL13431113	0.86	ROCK2 (0.47)	ROCK2PIM1PIM3FFAR4MGLL
	SCHEMBL693720	0.83	MGLL (0.58)	ROCK2PIM1PIM3FFAR4MGLL
	SCHEMBL1356786	0.83	FFAR4 (0.47)	ROCK2PIM1PIM3FFAR4MGLL
	SCHEMBL4282844	0.82	ENPP3 (0.56)	FFAR4MGLLENPP3CDC7ALB
	SCHEMBL1356949	0.81	PLA2G10 (0.54)	ROCK2PIM1PIM3POLBTDP1
	SCHEMBL6840254	0.80	ROCK2 (0.76)	ROCK2PIM1PIM3POLBTDP1
	SCHEMBL27403900	0.79	CDC7 (0.50)	ROCK2PIM1PIM3FFAR4MGLL
	SCHEMBL13243745	0.78	ROCK2 (0.51)	ROCK2PIM1PIM3POLBTDP1
	SCHEMBL6292916	0.78	FFAR4 (0.43)	FFAR4MGLLENPP3CDC7ALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.