SCHEMBL1357656

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL24685633	0.84	ABL1 (0.66)	ABL1SIGMAR1KDM4EHTTSMN1; SMN2
	SCHEMBL1356743	0.83	ABL1 (0.65)	ABL1SIGMAR1LMNAKDM4EALDH1A1
	SCHEMBL1356468	0.82	SIGMAR1 (1.00)	ABL1SIGMAR1ALDH1A1ENPP2
	SCHEMBL1356838	0.82	SIGMAR1 (1.00)	ABL1SIGMAR1ALDH1A1ENPP2
	SCHEMBL17965439	0.81	ABL1 (0.60)	ABL1SIGMAR1LMNAKDM4EHTT
	SCHEMBL25736178	0.81	ABL1 (0.62)	ABL1SIGMAR1KDM4EALDH1A1HTT
	SCHEMBL1357556	0.80	SIGMAR1 (0.80)	ABL1SIGMAR1ALDH1A1ENPP2TSHR
	SCHEMBL1356999	0.80	SIGMAR1 (0.80)	ABL1SIGMAR1KDM4EALDH1A1ENPP2
	Oxalic Acid SCHEMBL1356977	0.80	ABL1 (0.58)	ABL1SIGMAR1LMNAKDM4EHTT
	SCHEMBL17965435	0.79	SIGMAR1 (0.66)	ABL1SIGMAR1KDM4EALDH1A1ELOVL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.