SCHEMBL1356743

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8473697	0.90	ABL1 (0.53)	ABL1SIGMAR1POLBMAPTELOVL1
	SCHEMBL1356872	0.87	ABL1 (0.60)	ABL1SIGMAR1MAPTNOTUMELOVL1
	SCHEMBL1357656	0.83	ABL1 (0.73)	ABL1SIGMAR1MAPTNOTUMELOVL1
	SCHEMBL24685633	0.82	ABL1 (0.66)	ABL1SIGMAR1POLBMAPTNOTUM
	SCHEMBL1356884	0.81	SIGMAR1 (0.63)	ABL1SIGMAR1POLBMAPTKDM4E
	SCHEMBL1357515	0.81	ABL1 (0.58)	ABL1SIGMAR1MAPTELOVL1CACNA1G
	SCHEMBL1356441	0.81	NPC1 (0.43)	ABL1SIGMAR1POLBMAPTCACNA1G
	SCHEMBL1356919	0.81	SIGMAR1 (0.52)	ABL1SIGMAR1POLBMAPTKCNH2
	Oxalic Acid SCHEMBL1356980	0.79	ABL1 (0.56)	ABL1SIGMAR1MAPTELOVL1CACNA1G
	SCHEMBL25736178	0.77	ABL1 (0.62)	ABL1SIGMAR1MAPTNOTUMELOVL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.