Water

Water

SCHEMBL1358129

C[N+]1(CCO)CCOCC1.[OH-]

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
SLC18A3 Q16572 1/20 0.39
APOBEC3A P31941 2/20 0.36
APOBEC3G Q9HC16 2/20 0.36
CDC25A P30304 1/20 0.36
PABPC1 P11940 2/20 0.35
TERT O14746 7/20 0.35
CHRNB2 P17787 1/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA7 P36544 1/20 0.34
CHRNA4 P43681 1/20 0.34
CTDSP1 Q9GZU7 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
USP2 O75604 1/20 0.33
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL868812 0.98 HPGD (0.42) HPGDALOX15SLC18A3APOBEC3AAPOBEC3G
Bromide SCHEMBL340045 0.95 HPGD (0.41) HPGDALOX15SLC18A3APOBEC3AAPOBEC3G
Hydrochloric Acid SCHEMBL7338246 0.95 HPGD (0.41) HPGDALOX15SLC18A3APOBEC3AAPOBEC3G
SCHEMBL10390898 0.91 HPGD (0.39) HPGDALOX15SLC18A3APOBEC3AAPOBEC3G
SCHEMBL14790594 0.84
SCHEMBL13197525 0.84 HPGD (0.47) HPGDALOX15APOBEC3AAPOBEC3GCDC25A
Hydrochloric Acid SCHEMBL3653366 0.82 HPGD (0.46) HPGDALOX15APOBEC3AAPOBEC3GCDC25A
Bromide SCHEMBL830312 0.82 HPGD (0.46) HPGDALOX15APOBEC3AAPOBEC3GCDC25A
SCHEMBL9935792 0.82 HPGD (0.47) HPGDALOX15APOBEC3AAPOBEC3GCDC25A
SCHEMBL4893881 0.79 SLC18A3 (0.47) SLC18A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230420266-A1 COMPOSITION FOR TREATING SEMICONDUCTOR AND METHOD FOR TREATING OBJECT TO BE TREATED FUJIFILM CORPORATION (JP) 2023-12-28 US claimed
WO-2022190903-A1 COMPOSITION FOR TREATING SEMICONDUCTOR AND METHOD FOR TREATING OBJECT-TO-BE-TREATED 富士フイルム株式会社 2022-09-15 WO claimed
US-4324879-A Process for the preparation of polyisocyanates containing isocyanurate groups and the use thereof BAYER AKTIENGESELLSCHAFT (DE) 1982-04-13 US claimed
US-4227879-A ISOLATING THE DIAZONIUM SALT OF P-(P-AMINOPHENYL)AZO BENZENESULFONIC ACID AND COUPLING WITH 6-AMINO-1-NAPHTHOL-3-SULFONIC ACID AMERICAN COLOR & CHEMICAL CORPORATION (US) 1980-10-14 US claimed
EP-4748481-A1 METHOD FOR TREATING EXHAUST GAS Covestro Deutschland AG (DE) 2026-05-27 EP disclosed
WO-2025087730-A1 METHOD FOR PREPARING A POLYISOCYANATE BASED ON 1,5-PENTAMETHYLENE DIISOCYANATE COVESTRO DEUTSCHLAND AG (DE) 2025-05-01 WO disclosed
EP-4545579-A1 PROCESS FOR THE PREPARATION OF A POLYISOCYANATE BASED ON 1,5-PENTAMETHYLENE DIISOCYANATE Covestro Deutschland AG (DE) 2025-04-30 EP disclosed
US-20230420266-A1 COMPOSITION FOR TREATING SEMICONDUCTOR AND METHOD FOR TREATING OBJECT TO BE TREATED FUJIFILM CORPORATION (JP) 2023-12-28 US disclosed
WO-2022190903-A1 COMPOSITION FOR TREATING SEMICONDUCTOR AND METHOD FOR TREATING OBJECT-TO-BE-TREATED 富士フイルム株式会社 2022-09-15 WO disclosed
CN-107406573-B Polyisocyanate composition based on 1, 5-pentamethylene diisocyanate 科思创德国股份有限公司 2021-09-03 CN disclosed
EP-3271432-B1 POLYISOCYANATE COMPOSITION BASED ON 1,5-PENTAMETHYLENDIISOCYANATE COVESTRO DEUTSCHLAND AG (DE) 2019-07-31 EP disclosed
EP-2389403-B1 CASTINGS BASED ON POLYURETHANE COVESTRO DEUTSCHLAND AG (DE) 2018-04-04 EP disclosed
US-6627726-B1 Polyisocyanatoisocyanurate comprising less than 10% allophanate groups; reactive compound to make polyurethanes, polyureas, polyamides, and/or polythiourethanes; wear and acid resistance BASF AKTIENGESELLSCHAFT (DE) 2003-09-30 US disclosed
EP-0649866-A1 Lacquer polyisocyanates and their use BAYER AG (DE) 1995-04-26 EP disclosed
EP-0047452-B1 PROCESS FOR THE PREPARATION OF ISOCYANURATES CONTAINING ISOCYANATE GROUPS THE PRODUCTS OBTAINED BY THE PROCESS AND THEIR APPLICATION AS ISOCYANATE COMPONENT IN POLYURETHANE LACQUERS BAYER AG (DE) 1984-03-21 EP disclosed
US-4419513-A FROM HEXAMETHYLENE DIISOCYANATE AND ISOPHOR-ONE DIISOCYANATE BAYER AKTIENGESELLSCHAFT (DE) 1983-12-06 US disclosed
US-4324879-A Process for the preparation of polyisocyanates containing isocyanurate groups and the use thereof BAYER AKTIENGESELLSCHAFT (DE) 1982-04-13 US disclosed
EP-0047452-A1 Process for the preparation of isocyanurates containing isocyanate groups the products obtained by the process and their application as isocyanate component in polyurethane lacquers BAYER AG (DE) 1982-03-17 EP disclosed
US-4227879-A ISOLATING THE DIAZONIUM SALT OF P-(P-AMINOPHENYL)AZO BENZENESULFONIC ACID AND COUPLING WITH 6-AMINO-1-NAPHTHOL-3-SULFONIC ACID AMERICAN COLOR & CHEMICAL CORPORATION (US) 1980-10-14 US disclosed
EP-0010589-A1 Process for preparing polyisocyanates with isocyanate groups and their use as isocyanate components in polyurethane varnishes BAYER AG (DE) 1980-05-14 EP disclosed