Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WHR1 | P49842 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ACP1 | P24666 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PTGFR | P43088 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PRNP | P04156 | 1/20 | 0.41 |
| ▸ | MAT2A | P31153 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24702677 | 0.89 | MEN1 (0.55) | WHR1MEN1KMT2AATMMAPT | |
| SCHEMBL24702577 | 0.80 | MEN1 (0.49) | WHR1MEN1KMT2AATMMAPT | |
| SCHEMBL18698080 | 0.79 | KDM4E (0.69) | WHR1MEN1KMT2AATMMAPT | |
| SCHEMBL1102420 | 0.77 | KDM4E (0.61) | MEN1KMT2AATMMAPTKDM4E | |
| SCHEMBL18455642 | 0.76 | PRNP (0.63) | WHR1MEN1KMT2AATMMAPT | |
| SCHEMBL13585302 | 0.76 | MAPK1 (0.65) | WHR1MEN1KMT2AATMMAPT | |
| SCHEMBL28298102 | 0.76 | KMT2A (0.71) | WHR1MEN1KMT2AATMMAPT | |
| SCHEMBL23956547 | 0.76 | WHR1 (0.56) | WHR1MEN1KMT2AATMMAPT | |
| SCHEMBL24702579 | 0.76 | MEN1 (0.44) | WHR1MEN1KMT2AATMMAPT | |
| SCHEMBL15855093 | 0.75 | L3MBTL1 (0.58) | MEN1KMT2AMAPTHTTADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11708328-B2 | Organic electroluminescent compound and organic electroluminescent device comprising the same | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. | 2023-07-25 | — | — | US | disclosed |
| US-11708328-B2 | Organic electroluminescent compound and organic electroluminescent device comprising the same | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. | 2023-07-25 | — | — | US | disclosed |
| WO-2019066260-A1 | ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) | 2019-04-04 | — | — | WO | disclosed |
| US-9273012-B2 | Facile preparation of 4-substituted quinazolines and related heterocycles | UNIVERSITY OF HOUSTON SYSTEM (US) | 2016-03-01 | — | — | US | disclosed |
| WO-2012151141-A2 | A FACILE PREPARATION OF 4-SUBSTITUTED QUINAZOLINES AND RELATED HETEROCYCLES | UNIVERSITY OF HOUSTON SYSTEM (US) | 2012-11-08 | — | — | WO | disclosed |
| US-20120283436-A1 | FACILE PREPARATION OF 4-SUBSTITUTED QUINAZOLINES AND RELATED HETEROCYCLES | THE UNIVERSITY OF HOUSTON (US) | 2012-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11708328-B2 | Organic electroluminescent compound and organic electroluminescent device comprising the same | ELAVL1, TERT, VDAC2 | WHR1 1972/4885MEN1 2453/4885KMT2A 1734/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.