SCHEMBL1102420

SCHEMBL1102420

CC(C)c1ccc2nc(-c3ccccc3)c(-c3ccccc3)nc2c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 9/20 0.61
▸ ALDH1A1 P00352 8/20 0.61
▸ L3MBTL1 Q9Y468 4/20 0.61
▸ KMT2A Q03164 3/20 0.56
▸ ATM Q13315 1/20 0.56
▸ TLR9 Q9NR96 1/20 0.56
▸ LMNA P02545 5/20 0.52
▸ HPGD P15428 4/20 0.52
▸ MAPT P10636 2/20 0.52
▸ MCOLN3 Q8TDD5 1/20 0.52
▸ GAA P10253 4/20 0.51
▸ SMN1; SMN2 Q16637 2/20 0.51
▸ NPC1 O15118 1/20 0.51
▸ RAB9A P51151 1/20 0.51
▸ TDP1 Q9NUW8 3/20 0.50
▸ MEN1 O00255 2/20 0.50
▸ GPR55 Q9Y2T6 1/20 0.50
▸ NPSR1 Q6W5P4 1/20 0.46
▸ POLB P06746 1/20 0.45
▸ PDE10A Q9Y233 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18367038 0.83 NQO2 (0.54) KDM4EALDH1A1L3MBTL1KMT2ALMNA
SCHEMBL20025558 0.81 L3MBTL1 (0.57) KDM4EALDH1A1L3MBTL1KMT2ALMNA
SCHEMBL2706284 0.80 NPC1 (0.50) KDM4EALDH1A1L3MBTL1KMT2ALMNA
SCHEMBL12938128 0.80 NPC1 (0.50) KDM4EALDH1A1L3MBTL1KMT2ALMNA
SCHEMBL25900721 0.80 PSMB5 (0.60) KDM4EALDH1A1L3MBTL1KMT2AATM
SCHEMBL13585400 0.77 WHR1 (0.56) KDM4EALDH1A1L3MBTL1KMT2AATM
SCHEMBL1301829 0.77 ALDH1A1 (0.68) KDM4EALDH1A1L3MBTL1KMT2AATM
SCHEMBL10435353 0.76 KDM4E (0.65) KDM4EALDH1A1L3MBTL1KMT2AATM
SCHEMBL24702677 0.76 MEN1 (0.55) L3MBTL1KMT2AATMHPGDMAPT
SCHEMBL31070206 0.76 KDM4E (1.00) KDM4EALDH1A1L3MBTL1KMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11708328-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-07-25 — — US disclosed
US-11708328-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-07-25 — — US disclosed
US-20220399506-A1 ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-12-15 — — US disclosed
US-8962244-B2 Compounds for modulating RNA binding proteins and uses therefor UNIVERSITY OF MASSACHUSETTS (US) 2015-02-24 — — US disclosed
US-20130217685-A1 COMPOUNDS FOR MODULATING RNA BINDING PROTEINS AND USES THEREFOR UNIVERSITY OF MASSACHUSETTS (US) 2013-08-22 — — US disclosed
US-8377639-B2 Compounds for modulating RNA binding proteins and uses therefor UNIVERSITY OF MASSACHUSETTS (US) 2013-02-19 — — US disclosed
US-8153279-B2 Organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2012-04-10 — — US disclosed
US-20110065704-A1 COMPOUNDS FOR MODULATING RNA BINDING PROTEINS AND USES THEREFOR NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2011-03-17 — — US disclosed
US-20110065704-A1 COMPOUNDS FOR MODULATING RNA BINDING PROTEINS AND USES THEREFOR NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2011-03-17 — — US disclosed
US-7888863-B2 Organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2011-02-15 — — US disclosed
WO-2010151797-A2 COMPOUNDS FOR MODULATING RNA BINDING PROTEINS AND USES THEREFOR UNIVERSITY OF MASSACHUSETTS (US) 2010-12-29 — — WO disclosed
US-20100096982-A1 Novel organic electroluminescent compounds and organic electrouminescent device using the same GRACEL DISPLAY INC. (KR) 2010-04-22 — — US disclosed
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-03-04 — — US disclosed
US-20100045170-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-02-25 — — US disclosed
US-20100045170-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-02-25 — — US disclosed
US-20100033083-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-02-11 — — US disclosed
US-20090260686-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-10-22 — — US disclosed
US-20090230852-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-09-17 — — US disclosed
US-20090230852-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-09-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090260686-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OCIAD1, OCIAD2, FZD7 KDM4E 3940/4885ALDH1A1 706/4885L3MBTL1 1237/4885
US-20130217685-A1 COMPOUNDS FOR MODULATING RNA BINDING PROTEINS AND USES THEREFOR TIA1, ZFP3, RBM3 KDM4E 3175/4885ALDH1A1 3135/4885L3MBTL1 63/4885
US-20100096982-A1 Novel organic electroluminescent compounds and organic electrouminescent device using the same OCIAD1, OR10J3, ORMDL3 KDM4E 4170/4885ALDH1A1 208/4885L3MBTL1 479/4885
US-20100045170-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OCIAD1, OCIAD2, ORMDL3 KDM4E 3671/4885ALDH1A1 101/4885L3MBTL1 1193/4885
US-20090230852-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OXER1, L1CAM, RPL41 KDM4E 4525/4885ALDH1A1 1198/4885L3MBTL1 479/4885
US-11708328-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ELAVL1, TERT, VDAC2 KDM4E 684/4885ALDH1A1 838/4885L3MBTL1 239/4885
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same RPL36, RPL39, RPL36A KDM4E 4138/4885ALDH1A1 1477/4885L3MBTL1 1117/4885
US-20220399506-A1 ELECTROLUMINESCENT DEVICE L1CAM, LDHA, LDHB KDM4E 1597/4885ALDH1A1 442/4885L3MBTL1 457/4885
US-20110065704-A1 COMPOUNDS FOR MODULATING RNA BINDING PROTEINS AND USES THEREFOR TIA1, ZFP3, RBM3 KDM4E 3175/4885ALDH1A1 3135/4885L3MBTL1 63/4885
US-20100033083-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same ORMDL3, OCIAD2, OCIAD1 KDM4E 3367/4885ALDH1A1 1015/4885L3MBTL1 1629/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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