Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 11/20 | 0.64 |
| ▸ | F13A1 | P00488 | 2/20 | 0.51 |
| ▸ | TGM1 | P22735 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | ITK | Q08881 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29684447 | 0.90 | TGM2 (0.72) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL13581569 | 0.86 | TGM2 (0.73) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL39036 | 0.83 | TGM2 (0.72) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL13586723 | 0.81 | CYP19A1 (0.44) | TGM2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8459308 | 0.80 | TGM2 (0.57) | TGM2ALDH1A1CYP19A1RAB9A | |
| SCHEMBL81209 | 0.79 | TGM2 (1.00) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL13586719 | 0.78 | AKT1 (0.70) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL890715 | 0.78 | TGM2 (0.68) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL28240522 | 0.77 | TGM2 (0.96) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL30211836 | 0.77 | TGM2 (0.96) | TGM2F13A1TGM1LMNATGM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7625988-B2 | Maintain flexibility | WILLIAM MARSH RICE UNIVERSITY (US) | 2009-12-01 | — | — | US | disclosed |