Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TGM2 | P21980 | 2/20 | 0.39 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13581571 | 0.87 | TGM2 (0.46) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL3799021 | 0.85 | RAB9A (0.57) | KMT2AMEN1NPC1RAB9AKDM4E | |
| SCHEMBL4153167 | 0.81 | TGM2 (0.57) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL13586721 | 0.81 | TGM2 (0.64) | CYP19A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL13586718 | 0.75 | ELANE (0.41) | KMT2AMEN1NPC1RAB9AL3MBTL1 | |
| SCHEMBL3797430 | 0.75 | ALDH1A1 (0.53) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL13586719 | 0.72 | AKT1 (0.70) | KMT2AMEN1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL8767860 | 0.72 | RAD51 (0.44) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL12994621 | 0.72 | TGM2 (0.59) | KMT2AMEN1NPC1RAB9AKDM4E | |
| SCHEMBL29684447 | 0.70 | TGM2 (0.72) | CYP19A1KMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7625988-B2 | Maintain flexibility | WILLIAM MARSH RICE UNIVERSITY (US) | 2009-12-01 | — | — | US | disclosed |