SCHEMBL890715

SCHEMBL890715

C=CC(=O)Nc1ccc(C(=O)O)cc1

nearest known ligand 0.68

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 11/20 0.68
F13A1 P00488 2/20 0.63
TGM1 P22735 2/20 0.63
LMNA P02545 1/20 0.63
TGM3 Q08188 1/20 0.63
ALDH1A1 P00352 1/20 0.52
KMT2A Q03164 2/20 0.50
MITF O75030 1/20 0.50
MEN1 O00255 1/20 0.50
THRA P10827 1/20 0.49
THRB P10828 1/20 0.49
FFAR1 O14842 1/20 0.49
TP53 P04637 1/20 0.48
TSHR P16473 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydroxyl Radical SCHEMBL28150321 0.98 TGM2 (0.66) TGM2F13A1TGM1LMNATGM3
SCHEMBL21657888 0.90 TGM2 (0.56) TGM2F13A1TGM1LMNATGM3
SCHEMBL439369 0.87 TGM2 (0.79) TGM2F13A1TGM1LMNATGM3
SCHEMBL24510652 0.84 ALDH1A1 (0.52) TGM2F13A1TGM1LMNATGM3
SCHEMBL17327878 0.84 TGM2 (0.63) TGM2F13A1TGM1LMNATGM3
SCHEMBL29684447 0.83 TGM2 (0.72) TGM2F13A1TGM1LMNATGM3
SCHEMBL39036 0.83 TGM2 (0.72) TGM2F13A1TGM1LMNATGM3
SCHEMBL3633294 0.83 TGM2 (0.51) TGM2F13A1TGM1LMNATGM3
SCHEMBL6357758 0.82 TGM2 (0.61) TGM2F13A1TGM1LMNATGM3
SCHEMBL7470743 0.82 TGM2 (0.67) TGM2F13A1TGM1LMNATGM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 459 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115708891-B Developing drug-carrying microsphere based on microfluidic technology and preparation method and application thereof 四川大学 2024-06-18 CN claimed
CN-118184818-A Functionalized high molecular polymer, visualized embolism microsphere prepared by microfluidic technology and application 四川大学 2024-06-14 CN claimed
CN-104854123-B Copolymers for protein precipitation 默克专利股份公司 2020-04-21 CN claimed
EP-2935309-B1 COPOLYMERS FOR PROTEIN PRECIPITATION MERCK PATENT GMBH (DE) 2019-01-23 EP claimed
US-9926341-B2 Copolymers for protein precipitation MERCK PATENT GMBH (DE) 2018-03-27 US claimed
US-5871894-A CONTAINING CYAN DYE-FORMING COUPLER AND ADDITION COPOLYMER FUJI PHOTO FILM CO., LTD. (JP) 1999-02-16 US claimed
EP-0881535-A1 Silver halide color photographic light-sensitive material Fuji Photo Film Co., Ltd. (JP) 1998-12-02 EP claimed
US-4699867-A Radiation-sensitive positive working composition and material with aqueous-alkaline soluble acryamide or methacryamide copolymer having hydroxyl or carboxyl groups HOECHST AKTIENGESELLSCHAFT (DE) 1987-10-13 US claimed
CN-116496219-B Six-membered and five-membered heterocyclic compound, and pharmaceutical composition and application thereof 东南大学 2026-05-15 CN disclosed
US-RE50776-E1 Inhibitors of cyclin-dependent kinases DANA-FARBER CANCER INSTITUTE, INC. (US) 2026-02-03 US disclosed
WO-2025127092-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2025-06-19 WO disclosed
EP-4568954-A1 INHIBITORS OF CYCLIN-DEPENDENT KINASE (CDK) 12 AND/OR CDK13 AND USES THEREOF Insilico Medicine IP Limited (HK) 2025-06-18 EP disclosed
US-12331023-B2 Substituted heterocyclyl derivatives as CDK inhibitors AURIGENE ONCOLOGY LIMITED (IN) 2025-06-17 US disclosed
WO-2025076470-A1 SOX10 INHIBITORS AND USES THEREOF THE GENERAL HOSPITAL CORPORATION (US) 2025-04-10 WO disclosed
US-4940711-A Antihypertensive N-piperazinylalkanoylanilides RECORDATI, S.A., CHEMICAL AND PHARMACEUTICAL COMPANY (CH) 1990-07-10 US disclosed
US-4749647-A Polymerization-induced separation assay using recognition pairs GENETIC SYSTEMS CORPORATION (US) 1988-06-07 US disclosed
US-4699867-A Radiation-sensitive positive working composition and material with aqueous-alkaline soluble acryamide or methacryamide copolymer having hydroxyl or carboxyl groups HOECHST AKTIENGESELLSCHAFT (DE) 1987-10-13 US disclosed
EP-0120558-A1 Antihypertensive N-piperazinylalkanoylanilides RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) 1984-10-03 EP disclosed
US-4210582-A FIBER-REACTIVE YELLOW DYES FOR WOOL CIBA-GEIGY CORPORATION (US) 1980-07-01 US disclosed
US-4130702-A Polyacryloylaminobenzoic acid, polymethacryloylaminobenzoic acid and method of preparation CELANESE CORPORATION (US) 1978-12-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12331023-B2 Substituted heterocyclyl derivatives as CDK inhibitors CDK19, CDK9, CDK1 TGM2 3352/4885F13A1 2592/4885TGM1 2643/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.